The discovery of angiogenic growth factors: the contribution of Italian scientists [PDF]
, 2014 Angiogenesis is regulated, under both physiological and pathological conditions, by numerous “non-classic” pro-angiogenic factors, including fibroblast growth factor-2 (FGF-2), vascular endothelial growth factor (VEGF), and placental growth factor (PlGF),
Domenico Ribatti
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Rapamycin but not FK506 inhibits the proliferation of mononuclear phagocytes induced by colony-stimulating factors [PDF]
, 1994 FK506, CsA, and rapamycin are potent inhibitors of T lymphocyte activation; relatively little is known of their effects on cells of the monocyte/macrophage lineage.
Cooper, MH +3 more
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Canadian Journal of Infectious Diseases, 1991 Hematopoietic colony-stimulating factors coordinate the proliferation and maturation of bone marrow and peripheral blood cells during normal hematopoiesis.
James Rusthoven
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Scientific Reports, 2022 The human type II collagen (Col II), specifically expressed in chondrocytes, is a crucial component of the adult hyaline cartilage. We examine the potential of artificial induction of Col II in human peripheral blood mononuclear cells (PBMNCs) as a novel
Fu-Hui Wang +8 more
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Preclinical correction of human Fanconi anemia complementation group A bone marrow cells using a safety-modified lentiviral vector. [PDF]
, 2010 One of the major hurdles for the development of gene therapy for Fanconi anemia (FA) is the increased sensitivity of FA stem cells to free radical-induced DNA damage during ex vivo culture and manipulation.
Adair, J +10 more
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Effect in supralethally irradiated rats of granulocyte colony- stimulating factor and lisofylline on hematopoietic reconstitution by syngeneic bone marrow or whole organ passenger leukocytes [PDF]
, 1997 We have previously shown the existence of migratory hematopoietic stem cells in adult solid organs. This study demonstrates that granulocyte colony- stimulating factor (G-CSF) and lisofylline, a phosphatidic acid inhibitor that suppresses hematopoiesis ...
Abdul Rao +23 more
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Macrophage depletion disrupts immune balance and energy homeostasis. [PDF]
, 2014 Increased macrophage infiltration in tissues including white adipose tissue and skeletal muscle has been recognized as a pro-inflammatory factor that impairs insulin sensitivity in obesity.
Feng, Gen-Sheng +4 more
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Orientações para a prevenção da neutropenia febril em doentes submetidos a quimioterapia.
Acta Médica Portuguesa, 2008 Neutropenia and febrile neutropenia are common consequences of some cytotoxic chemotherapy regimens. This situation leads to modifications of the therapeutic regimen, conducting to either dose reduction or cycle delays.
Sérgio Barroso +11 more
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SAGE Open Medicine, 2021 Objectives: This study reports the levels of cytokines, chemokines, and growth factors previously identified as taking part in the pathology of atherosclerosis in human umbilical vein endothelial cells derived from mothers with type 2 diabetes and ...
Samar Sultan
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Granulocyte-activating mediators (GRAM) [PDF]
, 1988 In the present study we investigated the capability of human epidermal cells to generate granulocyte-activating mediators (GRAM). It could be shown that human epidermal cells as well as an epidermoid carcinoma cell line (A431) produce an epidermal cell ...
Kapp, A. +3 more
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