Results 41 to 50 of about 955,062 (292)

Hypothesis: Is yeast a clock model to study the onset of humans ageing phenotypes?

Frontiers in Oncology, 2012
In this paper we report the growth and ageing of yeast colonies derived from single cells isolated by micromanipulation and seeded one by one on separated plates to avoid growth interference by surrounding colonies.
Cristina eMazzoni, Cristina eMazzoni, Eleonora eMangiapelo, Eleonora eMangiapelo, Vanessa ePalermo, Vanessa ePalermo, Claudio eFalcone, Claudio eFalcone   +7 more
doaj   +1 more source

Geographic and chronographic variations of coloration in population of Polistes gallicus (Linnaeus, 1767) (Hymenoptera, Vespidae) [PDF]

Кавказский энтомологический бюллетень, 2005
The article presents the results of studying geographic and chronographic colour variability of paper wasp Polistes gallicus (Linnaeus, 1767) in Kherson Area of Ukraine in 2004-2005.
L.Yu. Rusina, L.A. Firman, .V. Skorokhod, A.V. Gilev   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Automated multigravity assist trajectory planning with a modified ant colony algorithm [PDF]

, 2010
The paper presents an approach to transcribe a multigravity assist trajectory design problem into an integrated planning and scheduling problem. A modified Ant Colony Optimization (ACO) algorithm is then used to generate optimal plans corresponding to ...
Vasile, Massimiliano, Ceriotti, Matteo
core   +4 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

The Socio-Political Crisis of the Siberian Region in the Post-February Period of the 1917 Revolution

Вестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2017
The paper considers the problem of the Siberian region general crisis of the 1917 spring. The internal and external contradictions of the transformation process of socio-economic and political relations in Siberia are examined in terms of the post ...
Mikhail I. Vtorushin
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source