Results 111 to 120 of about 6,134,800 (343)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Chromomagnetism in nuclear matter
, 2011 Quarks are color charged particles. Due to their motion there is a strong possibility of generation of color magnetic field. It is shown that however hadrons are color singlet particles they may have non-zero color magnetic moment.
A. Rùjula De +10 more
core +1 more source
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Results in EngineeringTi/Gf/Cf represents a novel form of hybrid fiber metal laminates (HFMLs) that successfully blend the benefits of titanium alloy, glass fiber reinforced plastic (GFRP), and carbon fiber reinforced plastic (CFRP). These materials have garnered attention in
Mohammadmahdi Negaresh +2 more
doaj +1 more source
Color symmetrical superconductivity in a schematic nuclear quark model
, 2009 In this note, a novel BCS-type formalism is constructed in the framework of a schematic QCD inspired quark model, having in mind the description of color symmetrical superconducting states.
Alford M. +7 more
core +1 more source
Molecular Oncology, EarlyView.Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source
Delving deeper into color space [PDF]
, 2018 So far, color-naming studies have relied on a rather limited set of color stimuli. Most importantly, stimuli have been largely limited to highly saturated colors.
Douven, Igor, Jraissati, Yasmina
core
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Basic & Clinical Cancer Research, 2019 Hyperthermia is a novel method for cancer therapy. To have the best control when heating tissues in hyperthermia, the use of magnetic nanoparticles is suggested.
Zahra Zahedi-Tabar +3 more
doaj +1 more source