Results 141 to 150 of about 7,230,535 (390)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Extreme THz fields from two-color filamentation of midinfrared laser pulses [PDF]

, 2018
Vladimir Yu. Fedorov, Stelios Tzortzakis
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

“Interface localization of reduced graphene oxide in polystyrene/polymethyl methacrylate blends with co-continuous morphology: Investigating the effects of polymer interface on nanoparticle network stabilization”

Results in Materials
This study aimed to investigate the co-continuous morphology of polymer blends and determine whether nanoparticles can be localized at the interface of polymers to create a well-organized network and decrease the percolation threshold.
Mohammadmahdi Negaresh, Azizeh Javadi, Hamid Garmabi   +2 more
doaj   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

A Study on the Color Prediction of Ancient Chinese Architecture Paintings Based on a Digital Color Camera and the Color Design System

Applied Sciences
Color paintings such as painted facades and interiors are important decoration elements of ancient Chinese architectures. The color of the paintings usually fades over time due to exposure to strong light, high humidity, high temperatures, and other ...
Guang Lv, Ningfang Liao, Chang Yuan, Lizhong Wei, Yunpeng Feng   +4 more
doaj   +1 more source

Efficient multi-angle polarimetric inversion of aerosols and ocean color powered by a deep neural network forward model

, 2021
Meng Gao, Bryan A. Franz, Kirk Knobelspiesse, Peng‐Wang Zhai, Vanderlei Martins, S. P. Burton, Brian Cairns, R. A. Ferrare, Joel Gales, Otto Hasekamp, Yongxiang Hu, Amir Ibrahim, Brent McBride, Anin Puthukkudy, P. Jeremy Werdell, Xiaoguang Xu   +15 more
openalex   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Investigation of Release Kinetics of DOX from Polydopamine Nanocapsules Prepared by Hard Template Method

Macromolecular Materials and Engineering
Development of smart drug delivery systems (DDSs) for effective delivering drugs to targeted areas and achieving controlled drug release (CDR) is critical for cancer chemotherapy.
Elahe Abdollahi, Vahid Haddadi‐Asl, Hanie Ahmadi, Mastoure Shirjandi, Fatemeh Khanipour   +4 more
doaj   +1 more source

Production of massive color-octet vector bosons at next-to-leading order [PDF]

, 2012
R. Sekhar Chivukula, Arsham Farzinnia, Elizabeth H. Simmons, Roshan Foadi   +3 more
openalex   +1 more source