Results 91 to 100 of about 1,806,417 (278)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Color standardization in whole slide imaging using a color calibration slide

open access: yesJournal of Pathology Informatics, 2014
Background: Color consistency in histology images is still an issue in digital pathology. Different imaging systems reproduced the colors of a histological slide differently.
Pinky A Bautista   +2 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Consistency of Students' Ideas across Evaporation, Condensation, and Boiling

open access: yes, 2013
Existing research on students' conceptions contain competing philosophical positions concerning the nature of students' ideas-whether those ideas are coherent, systematic and theory-like, or fragmented and incoherent.
Beeth, Michael Edward   +1 more
core   +1 more source

Categorical consistency of parity and magnitude facilitates implicit learning of color-number associations.

open access: yesPLoS ONE
Perceiving high-frequency stimulus pairings may lead to implicit associative learning. Interestingly, category-level pairings, such as blue-even, may facilitate implicit learning relative to item-level pairings, such as blue-2 and blue-7.
Talia L Retter, Christine Schiltz
doaj   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

An enhanced CycleGAN approach for landscape design: Style transfer and color harmonization

open access: yesAlexandria Engineering Journal
Style transfer and color optimization are critical aspects of landscape design, directly influencing the aesthetic and functional quality of design outputs.
Linglin Zhou
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Cross-species differences in color categorization [PDF]

open access: yes, 2006
International audienceBerlin and Kay (1969) found systematic restrictions in the color terms of the world's languages and were inclined to look to the primate visual system for their origin.
Davidoff, Jules B.   +10 more
core   +1 more source

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