Results 71 to 80 of about 5,576,489 (289)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Shining Lights on Limits: Optimizing Luminescent Solar Concentrators for Solar Windows

Advanced Photonics Research
The luminescent solar concentrator (LSC) can function as an electricity‐generating window whose performance is hindered by an inherent trade‐off between power conversion efficiency and visible light transmission.
Thomas A. de Bruin, Wilfried G. J. H. M. van Sark   +1 more
doaj   +1 more source

Advances in Nanomaterials-Based Color Conversion Layer

, 2022
Color conversion layer refers to a layer that converts the blue light emitted from the backlight into the red and green light. Heavy metal-free quantum dots and perovskite nanocrystals have attracted great attention as base materials for color conversion
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core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Extract Derived From Black Rice Functions as a Photothermal Agent for Suppressing Tumor Growth and Metastasis

Frontiers in Bioengineering and Biotechnology, 2020
It remains a challenge to develop an effective therapeutic agent with low cost and good biocompatibility for cancer therapy. Based on its dark color, we hypothesized that, the extraction from black rice grains, denoted BRE, could serve as a photothermal ...
Muzhou Teng, Shuyi Zhou, Rongjun Zhang, Yu Zhang, Yang Xu, Yang Xu, Xuemei Fu   +6 more
doaj   +1 more source

Technical efficiency and conversion to organic farming: the case of France [PDF]

Using a panel of French crop farms, we test whether farmers’ technical efficiency under conventional practices is a significant driver of conversion to organic farming.
Laure Latruffe, Céline Nauges
core  

Color-Tunable Light Emitting Diodes Based On Quantum Dot Suspension

, 2015
We propose a color-tunable light emitting diode (LED) consisting of a blue LED as the light source and quantum dot (QD) suspension as the color-conversion medium.
Chen, Haiwei, Luo, Zhenyue, Liu, Yifan, Xu, Su, Wu, Shin Tson   +4 more
core   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Enhanced color-conversion efficiency between colloidal quantum dot-phosphors and nitride LEDs by using nano-patterned p-GaN

, 2014
We have demonstrated that color-conversion efficiency can be enhanced through the use of non-radiative energy transfer between CdSe/ZnS core/shell colloidal quantum dots(QDs) and nitride multi-quantum well(MQW) in light emitting diodes(LEDs) having nano ...
Park, Min Joo, Choi, Kyoung Jin, Kwak, Joon Seop   +2 more
core   +1 more source