Results 121 to 130 of about 1,505,311 (244)

Severe ADEM‐Like Neuroinflammatory Disease and Cerebrovascular Fragility With Recurrent Pseudoaneurysms and Moyamoya in a Familial Germline CBL Mutation: Expanding the Clinical Phenotype

American Journal of Medical Genetics Part A, Volume 200, Issue 11, Page 2568-2574, November 2026.
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim, Anat Abramovich, Sara Via‐Dorembus, Gali Heimer, Bruria Ben‐Zeev, Etai Adam, Assaf A. Barg, Jonathan Roth, Basheer Sheick‐Yousif, Rony Beeri Berkowiz, Michal Feldon, Haim Bassan, Moran Hausman‐Kedem   +12 more
wiley   +1 more source

Fermented Noni Juice Supplementation Attenuates Heart Failure Development in Mice: Involvement of the Pentose Phosphate Pathway

Food Frontiers, Volume 7, Issue 6, November 2026.
ABSTRACT Morinda citrifolia L., commonly known as Noni, is a traditional medicinal plant that has long been utilized in various cultures for its anti‐inflammatory and antioxidant properties. Heart failure (HF) is a significant and growing public health concern worldwide that is characterized by substantial morbidity, mortality, and healthcare costs ...
Min Zhang, Xia Guan, Ruize Lu, Zhangxin Yu, Xuanjia Chen, Jingyao Xu, Guangying Chen, Haiying Zhang, Yan Liu   +8 more
wiley   +1 more source

Regional response of myocardial acceleration during isovolumic contraction during dobutamine stress echocardiography: a color tissue Doppler study and comparison with angiocardiographic findings.

, 2005
BACKGROUND: Color tissue Doppler imaging permits noninvasive quantitation of regional wall motion. In experimental studies, a new marker, the slope of the isovolumic contraction wave, isovolumic acceleration (IVA) was more insensitive to ventricular ...
Pauliks, LB;Vogel, M;Mädler, CF;Williams, RI;Payne, N;Redington, AN;Fraser, AG
core   +2 more sources

Valvular regurgitation by color doppler echocardiography

Arquivos Brasileiros de Cardiologia, 2000
André Schmidt, Oswaldo C. Almeida Fº, Antonio Pazin Fº, José A. Marin-Neto, Benedito C. Maciel   +4 more
doaj   +1 more source

Assessment of limited cardiac ultrasound to screen for mitral regurgitation

Echo Research and Practice
Background Mitral regurgitation (MR) is under-diagnosed and under-treated. Point-of-care ultrasound devices now include color Doppler technologies that can enhance the physical exam.
Divya Velury, Benjamin Koethe, Monica M. Dehn, Eileen Mai, Dikran R. Balian, Brian C. Downey, Arsalan Rafiq, Ayan R. Patel, Benjamin S. Wessler   +8 more
doaj   +1 more source

Value of acceleration flows and regurgitant jet direction by color Doppler flow mapping in the evaluation of mitral valve prolapse.

, 1990
To clarify the role of color Doppler echocardiography in the evaluation of mitral valve prolapse, we studied 49 consecutive patients in whom the sites of mitral valve prolapse were confirmed at the time of operation.
T Hozumi, K Yoshida, H Kato, J Yoshikawa, T Akasaka, Y Yamaura, M Shakudo   +6 more
core   +1 more source

Evaluation of a novel fetal echocardiography training programme in two tertiary care obstetric Centres

International Journal of Gynecology &Obstetrics, Volume 175, Issue 2, Page 771-778, November 2026.
Abstract Objectives Improving and maintaining high detection rates for major congenital heart disease (CHD) is a priority for successful prenatal anatomy screening programmes. The primary objective of this study was to evaluate the utility of on‐site multidimensional targeted training in fetal cardiac screening. Methods A prospective study evaluating a
Fiona Cody, Orla Franklin, Caoimhe Lynch, Zara Molphy, Patrick Dicker, Fergal Malone, Fionnuala M. Breathnach   +6 more
wiley   +1 more source

The Senokine Gas6 Promotes Aortic Valve Calcification Through CaMKII–DRP1–Mediated Terminal Scission of Mitochondrial‐Derived Vesicles

Aging Cell, Volume 25, Issue 11, November 2026.
In age‐associated calcific aortic valve disease (CAVD), human valve tissues and calcifying human valvular interstitial cells (hVICs) exhibit senescence‐associated features, while calcifying hVICs hypersecrete mitochondrial‐derived vesicles (MDVs). Donut‐shaped mitochondria serve as physical platforms for MDV budding, whereas Gas6 promotes Ca2+–CaMKII ...
Yaoyu Zhang, Jialiang Zhang, Yanjiani Xu, Wenhua Lei, Fei Xu, Junli Li, Zisong Wei, Bo Su, Shuang Liu, Jing Zhou, Hongde Li, Junpeng Ran, Weiya Li, Tuerhongjiang Tuerdi, Xiaojiao Wang, Zhi Fang, Fangyang Huang, Mao Chen   +17 more
wiley   +1 more source

Agreement between cardiac cycle time intervals and myocardial velocities measured by automated analysis of color tissue Doppler cine loops and by manual tracing of spectral pulsed‐wave tissue Doppler waveforms of sheep fetal heart under normal and pathological conditions: An experimental study

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 11, Page 2205-2220, November 2026.
Automated cTDI in sheep fetuses provided reproducible measurements of myocardial velocities and heart rate that align well with manual pulsed‐wave TDI. For cardiac cycle duration metrics, the two modalities are not interchangeable. These findings support that automated cTDI is well suited for longitudinal assessment under both physiological and ...
Juulia Lantto, Maria Grazia Morena, Heikki Huhta, Amar Bhide, Jonas Johnson, Juha Räsänen, Ganesh Acharya   +6 more
wiley   +1 more source

A Combination of Alleles in LMOD2 and a lncRNA is Strongly Associated With Myxomatous Mitral Valve Disease in Cavalier King Charles Spaniels

Animal Genetics, Volume 57, Issue 5, October 2026.
ABSTRACT A previous genome‐wide association study identified regions on canine chromosome (cfa) 13 and 14 associated with early onset myxomatous mitral valve disease (MMVD) in Cavalier King Charles Spaniels (CKCS). In the present study, whole genome sequencing (WGS) of 9 CKCS cases (mitral regurgitation (MR) before 4.5 years or congestive heart failure
Lisbeth Høier Olsen, Arney Eva Gunnlaugsdóttir, Majbritt Busk Madsen, Isabella Jane Larsen, Maria Josefine Ubbe Reimann, Foteini Papadaki, Ingrid Ljungvall, Jens Häggström, Torben Martinussen, Henrik Duelund Pedersen, Torkel Falk, Merete Fredholm, Peter Karlskov‐Mortensen   +12 more
wiley   +1 more source