Results 91 to 100 of about 2,007 (263)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Optimization of Mordant Dyeing Process of the Natural Dyestuff Extracted from Camellia oleifera Seed for Silk Fabric and Its Property

open access: yesJournal of Natural Fibers
The natural dyestuff extracted from Camellia oleifera seed was applied to dyeing silk fabric in this paper. In order to achieve both good dyeing effect and color fastness of silk fabric, five mordants were chosen to apply in its mordant dyeing process ...
Huaqing Wang, Hongqiang Yan
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Natural Dyeing of Bio-Mordanted Cellulosic Okra Fiber and Machine Learning–Based Prediction of Dyeing Characteristics

open access: yesJournal of Natural Fibers
In this research, okra fiber was extracted from okra plants by the biological degradation method. Cellulosic okra fibers were treated with sodium carbonate, and then the samples were dyed with natural dye obtained from madder with different ...
Seyda Eyupoglu   +3 more
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Coloring Cotton Fabrics by Pigment Printing Method with Reduction of Process Steps: An Innovative Approach

open access: yesDüzce Üniversitesi Bilim ve Teknoloji Dergisi
This study focuses on coloring cotton woven fabrics using pigment dyes with a printing technique, without applying the conventional scouring and bleaching processes typically involved in pre-treatment.
Emine Ayaz, Zeynep Ömeroğulları
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Modulation of Marigold Based Lutein Dye and its Dyeing Behaviour Using UV Radiation

open access: yesJournal of Natural Fibers, 2017
Application of natural dyes has increased interest in the past few years due to the eco-friendly behavior of these dyes. The present research is concerned with the effect of UV on dyeing behavior of cotton using marigold as source of natural Lutein dye ...
F. Rehman   +7 more
doaj   +1 more source

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