Results 71 to 80 of about 2,086 (263)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

A Research on the Colors Obtained from Rockrose Cistus laurifolius L. and Their Fastness Values

Journal of Agricultural Sciences, 2002
Rockrose is a plant of class Pareitales, family Cistaceae, genus cistus L. The aim of this research is to determine colors obtained from rockrose with different mordants and mordanting methods, these colors fastness values such as light, friction, wet ...
Filiz Nurhan Ölmez, Nuran Kayabaşı
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Eco-friendly coloration of linen to ameliorate its practical approach

MATEC Web of Conferences, 2017
Reactive dyes are the perfect choice for dyeing of cellulosic fibers due to produce a wide gamut of bright colors with excellent color fastness, however environmental pollution is increasing in recent days seeing that of making use of inorganic salt and ...
Pervez Md. Nahid, Inamdar Umarsharif Y., Talukder Md. Eman, Mahmud Sakil, Habib Md. Ahsan, Kamruzzaman Md., Cai Yingjie   +6 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Wood Extracts for Dyeing of Cotton Fabrics—Special View on Mordanting Procedures

Textiles
Natural dyes offer a bio-based opportunity to support the attractive coloration of textile fabrics made from natural fibers like cotton, wool, hemp, and many other textile materials.
Thanh Hoa Mai, Thomas Grethe, Boris Mahltig   +2 more
doaj   +1 more source

Development of functional wool fabric by treatment with aqueous and alkaline extracts of Cinnamomum camphora plant leaves

Journal of Natural Fibers, 2020
This work is carried out in search of natural alternatives to synthetic dyes capable of imparting functional properties. Natural dye from camphor plant (Cinnamomum camphora) was extracted under two extraction mediums: aqueous and alkaline.
Asfandyar Khan, Muhammad Tahir Hussain, Huiyu Jiang, Seema Gul   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source