Achieving Functional and Aesthetic Harmony Through a Fully Digital Workflow for Lateral Agenesis Rehabilitation: A 12-Month Follow-Up. [PDF]
Scotti CK +5 more
europepmc +1 more source
Harmony between color and fragrance
Kumiko MIURA, Miho SAITO
openaire +2 more sources
Osteosarcoma stemness is driven by the ITGB2‐COPS3‐SOX2 signaling axis. This study reveals that nuclear COPS3 stabilizes SOX2, which in turn undergoes liquid‐liquid phase separation to promote stemness. Based on this mechanism, a novel COPS3 inhibitor, Z‐5891, was developed, effectively suppressing tumor growth and stemness in vivo, offering a ...
Lei Guo +7 more
wiley +1 more source
From function to wellbeing: healing design strategies in contemporary outdoor fashion. [PDF]
Li Y, Kam S.
europepmc +1 more source
BiSCALE: A pathology‐driven deep learning framework for multi‐scale gene expression prediction from whole‐slide images. It accurately infers bulk and near‐cellular spot‐level expression, links predictions to clinical phenotypes, identifies disease‐associated niches, and enables applications in risk stratification and cell‐identity annotation, providing
Hailong Zheng +8 more
wiley +1 more source
From Muscular Hypertonus to Equilibrium: A Conceptual Framework for Aesthetic Neuromodulation Based on the Index of Muscular Equilibrium (IME). [PDF]
Armenti AF.
europepmc +1 more source
This study identifies mutation‐intolerant genes (MIGs), which are mutationally constrained in tumors despite normal‐tissue variability. Using miDriver, the authors pinpoint MIGs essential for tumor‐intrinsic fitness and immune evasion. Focusing on CHEK1, they show it drives tumor fitness and sculpts an immunosuppressive niche via the MIF–CD74 axis ...
Tao Wang +16 more
wiley +1 more source
Esthetic, Periodontal, and Functional Outcomes of Orthodontic Space Closure Versus Prosthetic Replacement for Congenitally Missing Maxillary Lateral Incisors: A Systematic Review. [PDF]
Althubaiti MM +13 more
europepmc +1 more source
Ultrathin‐Gold‐Resonators‐Enabled Bolometers with High Linearity, Responsivity, and Repeatability
This work demonstrates ultrathin gold nanomechanical resonators operating in HF/VHF bands, unveiling their potential for laser power sensing. By exploiting frequency shifts resulting from laser‐induced thermal tension, these devices can function as sensitive nanoscale bolometers, with outstanding linearity, responsivity, and repeatability. The findings
Jiaqi Wu +9 more
wiley +1 more source
A single-cell transcriptomic dataset profiling traumatic brain injury and NeuroD1-based gene therapy in mice. [PDF]
Chen R +9 more
europepmc +1 more source

