Results 81 to 90 of about 338,421 (294)
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
The annual flower trials were planted from 30 May through 4 June, 1999 in the Perennial Landscape and All America Selections Display Garden of the Georgeson Botanical Garden (64°51N, 147°52W). Fairbanks silt loam soil was fertilized with 1 0 -2 0 -2 0
Holloway, Patricia S. +4 more
core
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Decelerated spreading in degree-correlated networks
While degree correlations are known to play a crucial role for spreading phenomena in networks, their impact on the propagation speed has hardly been understood.
A. Barrat +3 more
core +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The Identification of the influential nodes in networks is one of the most promising domains. In this paper, we present an improved iterative resource allocation (IIRA) method by considering the centrality information of neighbors and the influence of ...
Liu, Jian-Guo +2 more
core +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Conclusions: Moist desquamations are more likely to occur in severe radiodermatitis in patients with head and neck cancer. Since they can fuse and spread, preventative measures to mitigate spreading are important.
Nao Miyamae +3 more
doaj +1 more source
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Optical vortices, beams that carry a twist, are pivotal in advanced technologies like optical manipulation, optical communications and imaging. However, their utility has been hampered by a fundamental limitation: the size and spread of the beam change ...
Tian Xia +8 more
doaj +1 more source

