Results 51 to 60 of about 340,880 (298)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Al-Kitab Journal for Pure Sciences, 2023 Poly methyl methacrylate (PMMA) is one of the most widely used materials in modern prosthodontics. It is widely known due to its simplicity in use and acceptable aesthetic.
Jaymin DhahirTaher +1 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
, 2018 A comparison was done regarding tertiary students' response between the symmetrical color wheel—The Itten Color Wheel developed by Johanne Itten at Bauhaus School and the asymmetrical Munsell Color Space developed by Professor Albert Munsell.
Woon Lam Ng, Ng, Woon Lam
core +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Sustainability in the Textile Sector: Wool Dyeing with Hydrolyzate from Black Soldier Fly
TextilesThe textile industries mostly rely on synthetic dyes, which contain nonbiodegradable components and high toxicity, making their use environmentally hazardous.
Ashish Vishawanath Mohod +5 more
doaj +1 more source
Dental Journal, 2005 Tooth crown restoration was made in a complex system consisting of several elements, namely tensile strength and shear strength bond between copper alloy and acrylic resin after tin plating.
Endanus Harijanto, Sri Yogyarti
doaj +1 more source
Estabilidade da cor de agentes cimentantes utilizados para facetas cerâmicas [PDF]
, 2010 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Odontologia, Florianópolis, 2010O objetivo deste estudo in vitro foi avaliar a estabilidade da cor de diferentes agentes ...
Pinto, Greciana Bruzi Brasil
core
, 2015 Colors have been found to affect psychological functioning. Empirical evidence suggests that, in test situations, brief perceptions of the color red or even the word "red" printed in black ink prime implicit anxious responses and consequently impair ...
Baumeister, Roy F. +6 more
core +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source