Results 101 to 110 of about 284,773 (249)
Medical Laboratory Journal, 2017 Background and Objectives: We studied effects of eight weeks of resistance training and IGF-1 injection on serum level of IGF-1, IGFBP-3 and IGF-1/IGFBP-3 ratio in Wistar rats.
Babisan Askari +2 more
doaj
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Emergency conditions of the colon and rectum are extremely common and all general surgeons must be competent at managing these conditions. Emergency colonic resections are a core skill and are needed for a variety of reasons such as perforated diverticulitis, obstructing tumours, colonic volvulus and fulminant colitis.
Reynolds, Ian, McNamara, Deborah
openaire +2 more sources
, 2014 FOLFOX4 (5-fluorouracil, leucovorin, and oxaliplatin) is a standard regimen for the treatment of advanced colorectal cancer. Its dose intensity and safety profile were compared between 2 Asian and 4 Western studies by analyzing 3359 patients.
Sugihara, Kenichi;Ohtsu, Atsushi;Shimada, Yasuhiro;Mizunuma, Nobuyuki;Lee, Po-Huang;de Gramont, Aimery;Goldberg, Richard M.;Rothenberg, Mace L.;Andre, Thierry;Brienza, Silvano;Gomi, Katsushige +1 more
core +1 more source
The Effect of Omega-3 Intake on Colorectal Cancer
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2022 Background and Objective: Colorectal cancer is one of the most common cancers among men and women in the world. Of all the risk factors of colorectal cancer, nutritional factors are among the most important and preventable risk factors.
N Razavi +4 more
doaj
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Une occlusion intestinale aiguë inhabituelle
The Pan African Medical Journal, 2015 L'insertion de corps étrangers intrarectal reste dans notre contexte, une curiosité et un tabou. Elle est le plus souvent volontaire par trouble du comportement, pour des fins sexuelles (érotisme ou agressions), pour auto-traiter une constipation ou pour
Ammar Mahmoudi, Abdelaziz Hamdi
doaj +1 more source