Results 351 to 360 of about 5,474,833 (393)

Comorbidities, Socioeconomic Status, and Colorectal Cancer Diagnostic Route.

open access: yesJAMA Netw Open
Pennisi F   +5 more
europepmc   +1 more source

Effect of colorectal cancer stem cells on the development and metastasis of colorectal cancer. [PDF]

open access: yesWorld J Gastrointest Oncol
Deng RZ   +6 more
europepmc   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang   +4 more
wiley   +1 more source

Mesenteric benign lymph node enlargement in colorectal cancer: Friend or foe? [PDF]

open access: yesTransl Oncol
Junwei W   +9 more
europepmc   +1 more source

Sortilin‐Mediated Rapid, Precise and Sustained Degradation of Membrane Proteins via mRNA‐Encoded Lysosome‐Targeting Chimera

open access: yesAdvanced Science, EarlyView.
The study identified sortilin as a promising LTR, enabling targeted degradation of oncogenic proteins through an mRNA‐encoded MedTAC strategy. In a mouse model, MedTACPTK7 reduced PTK7 by up to 80%, extended survival, and showed excellent pharmacokinetics without toxicity, providing a scalable platform for targeted therapies.
Xin Chang   +8 more
wiley   +1 more source

Language as a barrier to colorectal cancer screening in flanders: an ecological study. [PDF]

open access: yesArch Public Health
Van den Bergh S   +4 more
europepmc   +1 more source

HDAC6 and USP9X Control Glutamine Metabolism by Stabilizing GS to Promote Glioblastoma Tumorigenesis

open access: yesAdvanced Science, EarlyView.
Glioblastoma (GBM) growth relies on glutamine synthetase (GS), which is stabilized by histone deacetylase 6 (HDAC6) and deubiquitinated by ubiquitin‐specific peptidase 9, X‐linked (USP9X). HDAC6 promotes GS deacetylation, while USP9X removes its K48‐linked polyubiquitination, enhancing GS stability.
Go Woon Kim   +9 more
wiley   +1 more source

Colorectal cancer early screening: Dilemmas and solutions. [PDF]

open access: yesWorld J Gastroenterol
Wu D   +6 more
europepmc   +1 more source

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