Results 11 to 20 of about 187,247 (256)

Clinical Correlates of Health Preference and Generic Health-related Quality of Life in Patients with Colorectal Neoplasms [PDF]

open access: yes, 2013
Background: The aims of the study were to assess the health preference and health-related quality of life (HRQOL) in patients with colorectal neoplasms (CRN), and to determine the clinical correlates that significantly influence the HRQOL of patients ...
Poon, TCJ   +3 more
core   +2 more sources

K-ras and p53 mutations in colonic lavage fluid of patients with colorectal neoplasias [PDF]

open access: yes, 2001
Background: The adenoma-carcinoma sequence has its molecular basis in several gene mutations of which K-ras and p53 are of paramount importance. The aims of this study were to evaluate whether these genetic alterations can be detected in colonic lavage ...
Folwaczny, Christian   +3 more
core   +1 more source

Population screening for colorectal cancer means getting FIT:the past, present, and future of colorectal cancer screening using the fecal immunochemical test for hemoglobin (FIT) [PDF]

open access: yes, 2014
Fecal immunochemical tests for hemoglobin (FIT) are changing the manner in which colorectal cancer (CRC) is screened. Although these tests are being performed worldwide, why is this test different from its predecessors?
Halloran, SP   +7 more
core   +1 more source

Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion [PDF]

open access: yes, 2013
Background Prevalence of colorectal cancer (CRC) in the British Bangladeshi population (BAN) is low compared to British Caucasians (CAU). Genetic background may influence mutations and disease features.
Sengupta, N   +69 more
core   +1 more source

Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts [PDF]

open access: yes, 2013
Lynch syndrome (LS) is characterised by the development of colorectal cancer, endometrial cancer and various other cancers, and is caused by a mutation in one of the mismatch repair genes: MLH1, MSH2, MSH6 or PMS2.
Sampson, JR   +153 more
core   +1 more source

Colorectal neuroendocrine neoplasms : areas of unmet need

open access: yes, 2019
: The subject of colorectal neuroendocrine neoplasms (NENs), subdivided into well-differentiated NENs, termed neuroendocrine tumours (NETs; grade (G) 1 and 2), and poorly differentiated NENs, termed neuroendocrine carcinomas (NECs; G3) according to the ...
Arnold, Rudolf   +55 more
core   +4 more sources

Epigenetics in diagnosis, prognostic assessment and treatment of cancer:An update [PDF]

open access: yes, 2014
Cancer cells contain multiple genetic and epigenetic changes. The relative specificity of many epigenetic changes for neoplastic cells has allowed the identification of diagnostic, prognostic and predictive biomarkers for a number of solid tumors and ...
Crook, Tim   +4 more
core   +1 more source

Risk of advanced colorectal neoplasia according to age and gender. [PDF]

open access: yes, 2011
Colorectal cancer (CRC) is one of the leading causes of cancer related morbidity and death. Despite the fact that the mean age at diagnosis of CRC is lower in men, screening by colonoscopy or fecal occult blood test (FOBT) is initiated at same age in ...
Alexander Crispin   +15 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Molecular analysis of appendiceal mucinous cystadenoma and rectal adenocarcinoma in a patient with urothelial carcinoma: a case report

open access: yes, 2013
Introduction: In this report, we present the case of a patient affected by appendiceal cystadenoma, a colorectal adenocarcinoma, and a concomitant bladder carcinoma, as well as the results of the molecular study of the most relevant mutational pathways ...
Cossu, Antonio   +6 more
core   +1 more source

Home - About - Disclaimer - Privacy