Results 241 to 250 of about 3,282,422 (392)

A commentary on ‘Incidence, prevention, risk factors, and prediction of venous thromboembolism in Chinese patients after colorectal cancer surgery: a prospective, multicenter cohort study’

, 2023
Yongjing Zhang, Qiuping Li, Hongmei Li
openalex   +1 more source

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

Advanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi, Yue Qi Ong, Prativa Majee, Esther SM Wong, Amhed Missael Vargas Velazquez, Kerem Fidan, Pierce Kah‐Hoe Chow, Wai Leong Tam, Ker Kan Tan, Iain Beehuat Tan, Vinay Tergaonkar   +10 more
wiley   +1 more source

Endoscopic Tattooing Using Indocyanine Green (ICG) Fluorescence for Intraoperative Guidance in Colorectal Surgery: Review of the Literature. [PDF]

Cancers (Basel)
Seretis F, Panagaki A, Tziatzios G, Gkolfakis P, Romanou E, Papastergiou V, Theodorou A, Kapiris A, Theodorou D, Triantafyllou T, Kapiris S, Paraskeva K.   +11 more
europepmc   +1 more source

GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer

Advanced Science, EarlyView.
Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello, Sandra Hauser, Michael Seifert, Christopher K. Barlow, Joel R. Steele, Emma Salisbury, Daniel Croagh, Kathryn S. Stok, Anna V. Taubenberger, Ralf B. Schittenhelm, Daniela Loessner   +10 more
wiley   +1 more source

Reducing surgical site infection in emergency colorectal surgery: the case for topical tranexamic acid. [PDF]

Int J Colorectal Dis
Gosavi R, Ooi G, Nguyen TC, Teoh W, Narasimhan V.   +4 more
europepmc   +1 more source

USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

Advanced Science, EarlyView.
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen, Ling Wang, Hongmei Fan, Lisheng Li, Lingyu Zhang, Ruoxin Li, Fang Liu, Fuli Wen, Yunbin Ye, Chuanzhong Huang   +9 more
wiley   +1 more source

Improving Compliance and Satisfaction With Quality Coffee Intake to Enhance Bowel Recovery After Colorectal Surgery: A Feasibility Study. [PDF]

Health Sci Rep
Delabays C, Grass F, Demartines N, Hahnloser D, Hübner M.   +4 more
europepmc   +1 more source

Low blood orexin concentration as a predictor of increased nutritional risk and all-cause mortality after surgery for colorectal cancer

Krzysztof Tojek, Damian Czarnecki, Marcin Ziółkowski, Małgorzata Michalska, Ewa Żekanowska, Natalia Mysiak, Łukasz Wołowiec, Jacek Budzyński   +7 more
openalex   +1 more source

Clinical outcomes and inflammatory response to single‐incision laparoscopic (SIL) colorectal surgery: a single‐blinded randomized controlled pilot study [PDF]

, 2018
David W Borowski, Elizabeth A. Baker, Deborah Wilson, D. K. Garg, TS Gill   +4 more
openalex   +1 more source

Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion

Advanced Science, EarlyView.
FUT8‐mediated core fucosylation of CD47 at N111 blocks SMURF1 binding and reduces CD47 ubiquitination and degradation. Blocking N111 glycosylation reduces CD47 expression and promotes macrophage phagocytosis of tumor cells. Furthermore, ablating CD47 core fucosylation boosts CD103+ dendritic cells (DCs) infiltration, increases natural killer (NK) cell ...
Yuting Cao, Siyuan Chai, Mingyang Li, Xiaoming Chen, Jiating Hu, Bingyi Lin, Liming Wu, Wen Yi, Qiang Zhu   +8 more
wiley   +1 more source