Results 261 to 270 of about 3,157,739 (436)

KRAS mRNA Spleen‐Targeting Lipid Nanoparticles Synergize with Irinotecan Silicasomes to Robustly Augment the Cancer Immunity Cycle in Pancreatic Cancer

Advanced Science, EarlyView.
To overcome pancreatic cancer's immunosuppressive barriers, this study explores a dual approach: triggering immunogenic tumor cell death at the primary tumor site with irinotecan‐loaded silicasomes and enhancing immune activation in the spleen using LNPs encapsulating tumor antigen mRNA and a TLR7/8 agonist.
Lijia Luo, Xiang Wang, Yu‐Pei Liao, Andre E. Nel   +3 more
wiley   +1 more source

Superior mesenteric artery syndrome following colorectal surgery: a systematic review. [PDF]

Ann Med Surg (Lond)
Alsaleh N, Yaseen W, Alshamat RA, Aljurushi R, Alshareef B.   +4 more
europepmc   +1 more source

Evaluation of Oral Administration of Antibiotics for Preoperative Bowel Preparation in Colorectal Surgery. In Reference to Combination of Antibiotecs and Duration of Administration.

, 2000
S. Osada, Satoshi Ono, Suefumi Aosasa, Chikara Ueno, Hiroshi Mochizuki   +4 more
openalex   +2 more sources

High serum YKL‐40 level after surgery for colorectal carcinoma is related to short survival [PDF]

, 2002
C. Cintin, Julia S. Johansen, Ib Jarle Christensen, Paul A. Price, Steen Sørensen, Hans Jørgen Nielsen   +5 more
openalex   +1 more source

Tumor Small Extracellular Vesicle‐Transmitted LncRNA CATED Promotes Platinum‐Resistance in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Overcoming platinum resistance in high‐grade serous ovarian cancer (HGSOC) is critical for improving outcomes. This study identifies lncRNA CATED, elevated in platinum‐resistant small extracellular vesicles (sEVs) and tumors, which drives cisplatin resistance by enhancing DHX36 SUMOylation, boosting RAP1A translation, and activating MAPK signaling ...
Yi Liu, Hanyuan Liu, Chenchen Zhu, Yan Yang, Zhen Shen, Ge Shan, Liang Chen, Ying Zhou   +7 more
wiley   +1 more source

Applicability and results of the versius surgical robotic system in colorectal surgery: a systematic review of the literature. [PDF]

J Robot Surg
Gussago S, Balaphas A, Liot E, Meurette G, Toso C, Ris F, Meyer J.   +6 more
europepmc   +1 more source

WTAP Mediated m6A Modification Stabilizes PDIA3P1 and Promotes Tumor Progression Driven by Histone Lactylation in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study reveals a new mechanism by which PDIA3P1 regulates the progression of esophageal squamous cell carcinoma (ESCC). PDIA3P1 upregulates the expression of GLUT1 and HK2, promoting glycolysis and lactate production. Lactate upregulates the lactylation level of histone H4K8 and activates the transcription of target gene BMP7, ultimately ...
Tao Huang, Qi You, Jiawei Liu, Xuguang Shen, Dengjun Huang, Xinlu Tao, Zhijie He, Chengwei Wu, Xinran Xi, Shouqiang Yu, Feng Liu, Zhihao Wu, Wenjun Mao, Shaojin Zhu   +13 more
wiley   +1 more source

Long-term Results of Laparoscopic Surgery for Colorectal Cancer.

, 2001
Hirotoshi Hasegawa, Masahiko Watanabe, Seiichiro Yamamoto, Masaki Kitajima   +3 more
openalex   +2 more sources

Impact of socioeconomic deprivation on outcome after surgery for colorectal cancer [PDF]

, 2002
David Hole, C S McArdle
openalex   +1 more source

ROS‐Responsive Hydrogel for Localized Delivery of Nampt and Stat3 Inhibitors Exhibits Synergistic Antitumor Effects in Colorectal Cancer Through Ferroptosis Induction and Immune Microenvironment Remodeling

Advanced Science, EarlyView.
In this study, ferroptosis in colorectal cancer cells is induced by FK866 through the NAD⁺/STAT3/GPX4 pathway. To minimize systemic toxicity, a reactive oxygen species (ROS)‐responsive hydrogel is developed to co‐deliver FK866 and C188‐9, resulting in synergistic and localized antitumor effects.
Chenyang Ye, Mi Mi, Saimeng Shi, Lina Qi, Shanshan Weng, Lu Wang, Yier Lu, Chao Chen, Yinuo Tan, Mengyuan Yang, Cheng Guo, Rui Bai, Xuefeng Fang, Ji Wang, Ying Yuan   +14 more
wiley   +1 more source