Results 51 to 60 of about 320,797 (292)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Elucidation of the Effect of Solar Light on the Near-Infrared Excitation Raman Spectroscopy-Based Analysis of Fabric Dyes

Molecules
Colored textiles are valuable physical evidence often found at crime scenes. Analysis of the chemical structure of textiles could be used to establish a connection between fabric found at a crime scene and suspect cloths.
Shannon Bober, Dmitry Kurouski
doaj   +1 more source

Effects of Light Exposure, Bottle Colour and Storage Temperature on the Quality of Malvasia delle Lipari Sweet Wine

Foods, 2021
The influence of light exposure, bottle color and storage temperature on the quality parameters of Malvasia delle Lipari (MdL) sweet wine were investigated.
Elena Arena, Valeria Rizzo, Fabio Licciardello, Biagio Fallico, Giuseppe Muratore   +4 more
doaj   +1 more source

Thermal comfort in the historical urban canyon: the effect of innovative materials [PDF]

, 2017
Urban heat island (UHI) can considerably affect the thermal quality of the urban environment, especially within urban canyons, that have typically low sky view factor and limited surface heat re-emission capability.
Castaldo, Veronica Lucia, Cotana, Franco, De Lieto Vollaro, Andrea, Ferrero, Marco, Golasi, Iacopo, Piselli, Cristina, Pisello, Anna Laura, Rosso, Federica, Salata, Ferdinando   +8 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Studies on Changes in Color and Flavor of Sake caused by Exposure to Light and Storage

JOURNAL OF THE SOCIETY OF BREWING,JAPAN, 1969
清酒にフェノール系, インドール系化合物, その他の還元性物質の標準品を添加して, 日光照射時の着色と日光臭の発生, 貯蔵時の着色と老ね香の発生をしらべ次の結果を得た。1.照射フラスコの上部空間を窒素ガス置換すると, 日光着色は抑制されるが, 日光臭の発生が促進される。貯蔵に対しては窒素ガス置換の有無は影響しない。2.日光着色は2価, 3価のフェノール系化合物の大部分, OH置換基を有するインドール系化合物, インドール, スカトール, インドール酢酸, アンスラ論ル酸, 3-ヒドμ キシアンスラニル酸.キヌレン酸, キサントレン酸デフェリフェリクリシンの添加によって促進され, フェルラ酸, カフェ酸アスコルビン酸エリソルピン酸ナトリウムによって抑制された。3.日光臭の発生はアスコルビン酸 ...
Shin SATO, Kin-ichi NAKAMURA, Makoto TADENUMA, Tetsuo HASUO, Koji MOTEGI   +4 more
openaire   +8 more sources

Diagnosis and management of vulvar Darier disease: A case report

Case Reports in Women's Health, 2023
Darier disease is an autosomal dominant disorder with hyperkeratotic papules affecting primarily seborrheic areas of the upper chest, back, forehead, scalp, nasolabial folds, ears, and, less frequently, the oral mucosa.
Ipek Evruke, Funda Gungor Ugurlucan, Begum Yeni Erdem, Sule Ozturk Sari   +3 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The color quality of Sumatra barb Puntigrus tetrazona (Bleeker, 1855) in different light spectrum exposure

Jurnal Iktiologi Indonesia, 2020
The color quality of Sumatra barb that cultivated by the farmers are not as good as the fish that collected from the wild. One of the causes is the unsuitable environment for maintaining and breeding Sumatran barb. This research aims to compare color quality of Sumatra barb Puntigrus tetrazona by exposure the different light spectrums on maintenance ...
Wijianto Wijianto, Kukuh Nirmala, Yuni Puji Hastuti, Eddy Supriyono   +3 more
openaire   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source