Results 121 to 130 of about 463,572 (293)
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Good Intentions Aren\u27t Enough: Intellectuals and Violence in Luis Goytisolo\u27s \u3cem\u3eMzungo\u3c/em\u3e [PDF]
In the 1990s Luis Goytisolo explores the possibilities of popular fiction, adapting various genres (travel, mystery, erotic, historical) to accomodate his long-term project of unpacking Western Values. Indeed, Goytisolo’s flirtation with the best-selling
Carney, Terri
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
A new continuous ink jet system for digital ceramic decoration using water based dispersed ceramic pigment has been developed, that increases drastically the sustainability of the process.
Ceramicos S.A., Colores +1 more
doaj
Las intercalaciones rojas del Eoceno marino de Vic (Barcelona) [PDF]
En el estudio que se viene realizando sobre la Estratigrafía del Eoceno marino de Vic hemos podido observar intercalaciones rojas entre los materiales, siempre de colores claros (azul-grisáceos, beige o blanquecinos) que constituyen las diversas facies ...
Reguant, Salvador
core +1 more source
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Sin resumen.
Hugo Von Hofmannsthal
doaj
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking. [PDF]
Chen Z +12 more
europepmc +1 more source
Lugar: Estación Metro Colón ;Protagonistas:cátedra Metrovalencia ;Tipo de evento:exposiciónMartín García, S. (2011). La Cátedra Metrovalencia en Bellas Artes presenta la exposición "Libros Artísticos en un Metro de Colores". http://hdl.handle.net/10251/
Martín García, Sonia
core

