Results 51 to 60 of about 190,909 (304)

Methods to identify the unexplored diversity of microbial exopolysaccharides

Frontiers in Microbiology, 2015
Microbial exopolysaccharides (EPS) are a structurally very diverse class of molecules. A number of them have found their application in rather diverging fields that extend from medicine, food and cosmetics on the one side to construction, drilling and ...
Broder eRühmann, Jochen eSchmid, Volker eSieber   +2 more
doaj   +1 more source

2-LED-µSpectrophotometer for Rapid On-Site Detection of Pathogens Using Noble-Metal Nanoparticle-Based Colorimetric Assays

Applied Sciences, 2020
Novel point-of-care compatible methods such as colorimetric assays have become increasingly important in the field of early pathogen detection.
Cornelia Reuter, Matthias Urban, Manuel Arnold, Ondrej Stranik, Andrea Csáki, Wolfgang Fritzsche   +5 more
doaj   +1 more source

Facile preparation of Fe3O4@Pt nanoparticles as peroxidase mimics for sensitive glucose detection by a paper-based colorimetric assay

Royal Society Open Science, 2022
A simple strategy to rapidly detect glucose was developed by utilizing core (Fe3O4)–shell (Pt) magnetic nanoparticles (Fe3O4@Pt NPs) as a nanoenzyme and a paper-based colorimetric sensor.
Ye He, Panlin Wang, Xiaojing Chen, Yahuang Li, Jiajun Wei, Guoxi Cai, Kiyoshi Aoyagi, Wenxiang Wang   +7 more
doaj   +1 more source

Selectivity and specificity: pros and cons in sensing [PDF]

, 2016
Sensing using specific and selective receptors provides two very different but complementary strategies. This Sensor Issues article will discuss the merits and challenges of specific sensors, and selective sensors based on synthetic arrays.
Peveler, William J., Rotello, Vincent M., Yazdani, Mahdieh   +2 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Focal adhesions are foci for tyrosine-based signal transduction via GIV/Girdin and G proteins. [PDF]

, 2015
GIV/Girdin is a multimodular signal transducer and a bona fide metastasis-related protein. As a guanidine exchange factor (GEF), GIV modulates signals initiated by growth factors (chemical signals) by activating the G protein Gαi.
Ghosh, Pradipta, Kabir, Firooz, Kalogriopoulos, Nicholas, Lo, I-Chung, Lopez-Sanchez, Inmaculada, Midde, Krishna K, Wang, Honghui   +6 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Gold Nanoparticle-Based Colorimetric Strategies for Chemical and Biological Sensing Applications

Nanomaterials, 2019
Gold nanoparticles are popularly used in biological and chemical sensors and their applications owing to their fascinating chemical, optical, and catalytic properties.
Chia-Chen Chang, Chie-Pein Chen, Tzu-Heng Wu, Ching-Hsu Yang, Chii-Wann Lin, Chen-Yu Chen   +5 more
doaj   +1 more source

KIAA1429 mediates epithelial mesenchymal transition in sorafenib‐resistant hepatocellular carcinoma through m6A methylation modification

Cancer Medicine, 2023
Background Hepatocellular carcinoma (HCC) is a primary liver cancer with high mortality. The long‐term use of sorafenib, a targeted drug for hepatocellular carcinoma, will lead to drug resistance, and patients are prone to cancer metastasis, the ...
Ye Kuang, Yun Cheng, Jia Wang, Hongyan Li, Xianghong Cao, Yang Wang   +5 more
doaj   +1 more source

In Vitro Screening Test Using Leishmania Promastigotes Stably Expressing mCherry Protein [PDF]

, 2014
Transgenic Leishmania major and Leishmania donovani axenic promastigotes constitutively expressing mCherry were used for in vitro antileishmanial drug screening. This method requires minimal sample manipulation and can be easily adapted to automatic drug
Miguel A. Morales, Vacchina, Paola
core   +2 more sources