Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform
We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng +5 more
wiley +1 more source
Designing Tunable Paper-Based Colorimetric Sensor for Precise Detection of Hydrogen Peroxide Vapor. [PDF]
Hossain R, Apblett A, Materer NF.
europepmc +1 more source
Tailored Catalytic Microenvironments Enable Efficient Electrochemical Ammonia Production
This study shows that Co2+ substitution in inverse spinel FeFeCoO4 constructs an integrated catalytic microenvironment for efficient nitrate‐to‐ammonia reduction. Jahn–Teller distortion activates Fe sites for *H generation, while hard–soft acid–base regulated dual‐metal sites optimize proton‐coupled electron transfer and intermediate adsorption ...
Qi Zhang +8 more
wiley +1 more source
Quantification of the H-Bond-Donating Ability of Trifluoromethyl Ketone Hydrates Using a Colorimetric Sensor. [PDF]
Berlin CB +3 more
europepmc +1 more source
A Colorimetric Sensor Enabled with Heterogeneous Nanozymes with Phosphatase-like Activity for the Residue Analysis of Methyl Parathion. [PDF]
Zhao F, Li M, Wang L, Wang M.
europepmc +1 more source
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang +13 more
wiley +1 more source
Tb doped carbon dots as a platform for fluorescence ratiometric and colorimetric sensor for deferasirox. [PDF]
Latifi F, Amjadi M, Hallaj T, Alavi SMS.
europepmc +1 more source
Highly Selective Colorimetric Sensor of Mercury(II) Ions by Andrographolide-Stabilized Silver Nanoparticles in Water and Antibacterial Evaluation. [PDF]
Talodthaisong C +7 more
europepmc +1 more source
The ZnSm‐Cl dinuclear molecular complex was synthesized through a simple one‐pot method. ZnL and Sm3+ exhibit complementary temperature‐dependent emission As the temperature increases, a noticeable color difference of ZnSm‐Cl can be observed within the room temperature range of 253‐333 K.
Ye Xia +7 more
wiley +1 more source
Development of a chromene-based fluorescent and colorimetric sensor for the sensitive detection of calcium ions in a complex medium: a detailed DFT and experimental approach. [PDF]
Khurshid K +5 more
europepmc +1 more source

