Results 61 to 70 of about 61,204 (302)

Prussian Blue Nanoparticle Supported MoS₂ Nanocomposites as a Peroxidase-Like Nanozyme for Colorimetric Sensing of Dopamine

Biosensors, 2022
An abnormal level of dopamine (DA) is usually related to neurological disorders, including Parkinson’s disease. Herein, cubic-shaped, Prussian blue nanoparticle-supported MoS2 nanocomposites (MoS2-CPBNPs) were prepared as peroxidase-like nanozymes for ...
Zhiqiang Zhu, Lingbo Gong, Xiangyang Miao, Chaoyang Chen, Shao Su   +4 more
doaj   +1 more source

Textile-based wearable sensors for assisting sports performance [PDF]

, 2009
There is a need for wearable sensors to assess physiological signals and body kinematics during exercise. Such sensors need to be straightforward to use, and ideally the complete system integrated fully within a garment.
Coyle, Shirley, Diamond, Dermot, Lau, King-Tong, Morris, Deirdre, Moyna, Niall   +4 more
core   +1 more source

Recent Progress in Optical Sensors for Biomedical Diagnostics [PDF]

, 2020
In recent years, several types of optical sensors have been probed for their aptitude in healthcare biosensing, making their applications in biomedical diagnostics a rapidly evolving subject.
Altintas, Zeynep, Pirzada, Muqsit
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Inheritance of determinants of flower colour in tetraploid roses [PDF]

, 2009
The choice of selection breeding for crop improvement in cut roses requires a better understanding of biological mechanisms and knowledge of the inheritance of the major target traits which can lead to new or improved screening methods.
Gitonga, V.W., Keizer, L.C.P., Koning-Boucoiran, C.F.S., Krens, F.A., Ribot, S.A., Stolker, R.   +5 more
core   +3 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Nanomaterial-based optical colorimetric sensors for rapid monitoring of inorganic arsenic species: a review

Discover Nano
Health concerns about the toxicity of arsenic compounds have therefore encouraged the development of new analytical tools for quick monitoring of arsenic in real samples with improved sensitivity, selectivity, and reliability.
Kalayou Hiluf Gebremedhin, Mebrahtu Hagos Kahsay, Nigus Kebede Wegahita, Tesfamariam Teklu, Berihu Abadi Berhe, Asfaw Gebretsadik Gebru, Amanuel Hadera Tesfay, Abraha Geberekidan Asgedom   +7 more
doaj   +1 more source

Real-time sweat pH monitoring based on a wearable chemical barcode micro-fluidic platform incorporating ionic liquids [PDF]

, 2012
This work presents the fabrication, characterisation and the performance of a wearable, robust, flexible and disposable chemical barcode device based on a micro-fluidic platform that incorporates ionic liquid polymer gels (ionogels).
Beauchamp, Benito-Lopez, Benito-Lopez, Benito-Lopez, Byrne, Byrne, Byrne, Caroline Barry, Casa, Coleman, Corinne O’Toole, Cormac Fay, Dermot Diamond, Diamond, Diamond, Fernando Benito-Lopez, Granger, Jonsdottir, MacFarlane, Morgan, Morris, Neouze, Niall Moyna, O’Neill, O’Toole, Patterson, Patterson, Ramnial, Rehrer, Robert Byrne, Safavi, Sarah Hughes, Schmid-Wendtner, Seddon, Shirley Coyle, Smyth, Soller, Tamada, Vincenzo F. Curto, Wasserscheid, Weber, Whitesides   +41 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source