Results 21 to 30 of about 20,588 (248)

Emerging Cytokine Biosensors with Optical Detection Modalities and Nanomaterial-Enabled Signal Enhancement

open access: yesSensors, 2017
Protein biomarkers, especially cytokines, play a pivotal role in the diagnosis and treatment of a wide spectrum of diseases. Therefore, a critical need for advanced cytokine sensors has been rapidly growing and will continue to expand to promote clinical
Manpreet Singh   +3 more
doaj   +1 more source

Effect of a wear-resistant resin coat on the color stability of a resin-modified glass ionomer restorative material

open access: yesJournal of Indian Society of Pedodontics and Preventive Dentistry, 2021
Aim: The purpose of this in vitro study was to evaluate the effect of the Equia Forte Coat on the color stability of Equia Forte Fil. Materials and Methods: Sixty discs of Equia Forte Fil were randomly divided into two groups. One group of 30 samples was
Madhu Mohan   +2 more
doaj   +1 more source

Comparison of the Reproducibility of Various Tooth Color Measurement Techniques

open access: yesJournal of Dental School
Objective(s): Accurate shade selection is the most challenging step in the natural reconstruction of teeth in most cases. The most commonly used method for adapting the color of tooth and restorative materials is the visual matching of the tooth color ...
Marzieh Rohaninasab   +3 more
doaj   +1 more source

Synthesis of Fe-Doped Peroxidase Mimetic Nanozymes from Natural Hemoglobin for Colorimetric Biosensing and In Vitro Anticancer Effects

open access: yesBiosensors, 2023
Despite their efficiency and specificity, the instability of natural enzymes in harsh conditions has inspired researchers to replace them with nanomaterials.
Zahra Mohammadpour   +6 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Infant Milk Formulas: Effect of Storage Conditions on the Stability of Powdered Products towards Autoxidation

open access: yesFoods, 2015
Thirty samples of powdered infant milk formulas containing polyunsaturated fatty acids (PUFAs) have been stored at four different temperatures (20, 28, 40 and 55 °C) and periodically monitored for their malondialdehyde (MDA) content up to one year.
Stefania Cesa   +3 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Anatomical and Physicochemical Characterization of the Araucaria angustifolia Seed Coat

open access: yesFloresta e Ambiente, 2019
Seed coat plays an important role in the embryo protection and seed germination. This study aimed to characterize the anatomical structure, histochemical and physicochemical aspects of the seed coat of Araucaria angustifolia Kuntze.
Danielle Affonso Sampaio   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Paper-Based Analytical Device for Zinc Ion Quantification in Water Samples with Power-Free Analyte Concentration

open access: yesMicromachines, 2017
Insufficient sensitivity is a general issue of colorimetric paper-based analytical devices (PADs) for trace analyte detection, such as metal ions, in environmental water.
Hiroko Kudo   +4 more
doaj   +1 more source

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