Results 71 to 80 of about 67,832 (358)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Bidirectional Reflectance Measurement and Reflection Model Fitting of Complex Materials Using an Image-Based Measurement Setup

open access: yesJournal of Imaging, 2018
Materials with a complex visual appearance, like goniochromatic or non-diffuse, are widely used for the packaging industry. Measuring optical properties of such materials requires a bidirectional approach, and therefore, it is difficult and time ...
Aditya Sole   +3 more
doaj   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Determinação de zinco em solo utilizando colorimetria Determination of zinc in soil using colorimetry

open access: yesQuímica Nova, 2007
In terms of soil fertility, zinc is a micronutrient that is very important in the culture of soy, maize, rice and coffee, because it is a structural and functional component of a great number of enzymes.
Karina Fraige   +2 more
doaj   +1 more source

Temperature dependent characterization of optical fibres for distributed temperature sensing in hot geothermal wells

open access: yes, 2012
This study was performed in order to select a proper fibre for the application of a distributed temperature sensing system within a hot geothermal well in Iceland. Commercially available high temperature graded index fibres have been tested under in-situ
Albertsson A   +11 more
core   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung   +7 more
wiley   +1 more source

Electrochromic properties of a poly(dithienylfuran) derivative featuring a redox-active dithiin unit [PDF]

open access: yes, 2012
A teraryl monomer containing a 1,4-dithiin-furan central unit has been synthesised and characterised by single crystal X-ray crystallography. The di(thienyl)furan monomer 11 was successfully polymerised electrochemically and shown to possess a lower ...
Berridge, Rory   +7 more
core   +1 more source

Serum Uric Acid Levels in Older Adults: Associations With Clinical Outcomes and Implications for Reference Intervals in Those Aged 70 Years and Over

open access: yesArthritis Care &Research, EarlyView.
Objective Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged ≥70 years old.
Amanda J. Rickard   +15 more
wiley   +1 more source

Properties of thermally modified teakwood

open access: yesMaderas: Ciencia y Tecnología, 2021
Thermal modification is a treatment that seeks to improve the properties of wood and reduce the heterogeneity in its color. The objective of this work was to evaluate the effect of thermal treatment on the anatomical, chemical, physical, mechanical ...
Elaine Cristina Lengowski   +4 more
doaj  

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