Results 121 to 130 of about 1,340,224 (286)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

The Carina Project VII: Towards the breaking of the age-metallicity degeneracy of red giant branch stars using the c_UBI index

, 2014
We present an analysis of photometric and spectroscopic data of the Carina dSph galaxy, testing a new approach similar to that used to disentangle multiple populations in Galactic globular clusters (GCs).
Aparicio, A., Bono, G., Buonanno, R., Cassisi, S., Dall'Ora, M., Fabrizio, M., Ferraro, I., Gallart, C., Iannicola, G., Milone, A. P., Monelli, M., Nonino, M., Pulone, L., Stetson, P. B., Thévenin, F., Walker, A. R.   +15 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Research on the Accessibility of Different Colour Schemes for Web Resources for People with Colour Blindness

Journal of Imaging
This study is devoted to the analysis of the perception of colour schemes of web resources by users with different types of colour blindness (colour vision deficiency).
Daiva Sajek, Olena Korotenko, Tetiana Kyrychok   +2 more
doaj   +1 more source

The Las Campanas/AAT Rich Cluster Survey III: Spectroscopic Studies of X-ray Bright Galaxy Clusters at z~0.1

, 2005
[abridged] We present the analysis of the spectroscopic and photometric catalogues of 11 X-ray luminous clusters at z=0.07-0.16 from the Las Campanas / Anglo-Australian Telescope Rich Cluster Survey. Our spectroscopic dataset consists of over 1600 galaxy
Abell, Abell, Abraham, Abraham, Alastair C. Edge, Ann I. Zabludoff, Bailey, Balogh, Balogh, Balogh, Balogh, Balogh, Balogh, Balogh, Barnes, Batuski, Beers, Bekki, Bell, Bertin, Blake, Bower, Bruzual, Burstein, Burstein, Böhringer, Carlberg, Carlberg, Carlberg, Charlot, Christlein, Christlein, Colless, Colless, Couch, Couch, Danese, Dressler, Dressler, Dressler, Dressler, Dressler, Dressler, Drinkwater, Ebeling, Edge, Eileen O'Hely, Fasano, Fasano, Ferrari, Franx, Gerken, Gill, Girardi, Girardi, Girardi, Gray, Gunn, Gómez, Hogg, Huchra, Ian Smail, Jansen, Jones, Jones, Katgert, Kevin A. Pimbblet, Kodama, Kodama, Kodama, Kodama, Krick, Kurtz, Lacey, Landolt, Larson, Lavery, Lewis, Lewis, Mamon, Martini, Mink, Monet, Moore, Moran, O'Hely, O'Hely, Oemler, Ortiz-Gil, Osterbrock, Pimbblet, Pimbblet, Pimbblet, Pimbblet, Pimbblet, Poggianti, Poggianti, Press, Quilis, Rines, Schlegel, Searle, Smail, Smith, Terlevich, Terlevich, Thomas, Tonry, Treu, Visvanathan, Wake, Wake, Warrick J. Couch, Whitmore, Yahil, Zabludoff, Zabludoff, Zabludoff   +117 more
core   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Mass Transfer and Colour Analysis during Vacuum Frying of Colombian Coastal Carimañola. [PDF]

Int J Food Sci, 2020
Caro C AD, Sampayo R SP, Acevedo C D, Montero C P, Martelo RJ.   +4 more
europepmc   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Mapping the Milky Way bulge at high resolution: the 3D dust extinction, CO, and X factor maps

, 2014
Three dimensional interstellar extinction maps provide a powerful tool for stellar population analysis. We use data from the VISTA Variables in the Via Lactea survey together with the Besan\c{c}on stellar population synthesis model of the Galaxy to ...
Chen, B. Q., Enokiya, R., Fukui, Y., Gonzalez, O. A., Jiang, B. W., Minniti, D., Rejkuba, M., Schultheis, M., Torii, K.   +8 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source