Results 161 to 170 of about 304,855 (316)
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Generative modelling of continuous feature foraging reveals probabilistic representations of target distributions. [PDF]
Fuller JCM +3 more
europepmc +1 more source
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
From pen to paper-based screening: an early-stage colorimetric µPAD with desktop-app readout for lead and nitrite. [PDF]
Basu A, Asani PC, Nath K, Das S.
europepmc +1 more source
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Skin Colour in Salamanders Is Modulated by Both Epitranscriptomic Methylation and Gene Expression. [PDF]
Strowbridge N +3 more
europepmc +1 more source
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Biomimetic Surface Modification of Dental Zirconia via UV Irradiation for Enhanced Aesthetics and Wettability. [PDF]
Pan F +7 more
europepmc +1 more source

