Results 141 to 150 of about 161,509 (311)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Decoding ladybird's colours: Structural mechanisms of colour production and pigment modulation.

PLoS ONE
This study investigates the mechanisms underlying colour production in the family Coccinellidae, focusing on two model species: Adalia bipunctata (L.) and Calvia quatuordecimguttata (L.).
Marzia Carrada, Mohamed Haddad, Luis M San-Jose, Gonzague Agez, Jean-Marie Poumirol, Alexandra Magro   +5 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Effect of maturity and the colour parameters on the cocoa opening force using the existing mechanical system

Research in Agricultural Engineering
The study assessed the mechanical and colorimetric properties of cocoa (Theobroma cacao L.) pods at various maturity stages to improve the mechanised pod-opening efficiency.
Randy Amuaku, Eric Amoah Asante, Emmanuel Y.H Bobobee, Jerry Oppong Adutwum, Godwin Amanor   +4 more
doaj   +1 more source

Dissolved organic carbon and colour dynamics in drained and restored blanket peat [PDF]

, 2007
Peatlands are important terrestrial stores of carbon and a principal source of dissolved organic carbon (DOC) to the fluvial environment. Whilst often regarded as a net carbon sink, enhanced DOC concentrations and an associated rise in the level of water
Wallage, Zoe Elizabeth
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Assessing colour rendering properties of daylight sources

, 2008
The aims of this research are to develop an LED based high quality CIE-illuminant simulator, to investigate different visual methods for evaluating the colour rendering properties of different light sources, to test the current CIE colour rendering index
Li, Cheng
core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Interactions between luminance and colour signals : effects on shape

, 2013
This research was supported by the Engineering and Physical Sciences Research Council (EPSRC).Although luminance and color are thought to be processed independently at early stages of visual processing, there is evidence that they interact at later ...
Harris, Julie, Bloj, Marina, Clery, Stephane   +2 more
core   +1 more source