Results 121 to 130 of about 3,195,529 (338)
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
USE OF SELF-COMPACTING CONCRETE DURING RECONSTRUCTION OF THE BUILDING FOR THE ADMINISTRATION SERVICE CENTRE [PDF]
Twophase introduction of superplasticizer additive influence on the properties of concrete mixture was researched. The obtained results allowed concreting of strengthening for the columns building.
S. Bugayevskyi, Ye. Voronova, O. Shtefan
doaj
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Ubiquity and diversity of ammonia-oxidizing archaea in water columns and sediments of the ocean.
C. A. Francis +4 more
semanticscholar +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Stimulus-specific neuronal oscillations in orientation columns of cat visual cortex.
C. Gray, W. Singer
semanticscholar +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
A simple bijection between permutation tableaux and permutations
We present a simple a bijection between permutations of $\{1,..., n\}$ with $k$ descents and permutation tableaux of length $n$ with $k ...
Corteel, Sylvie
core +1 more source

