Results 91 to 100 of about 1,616,312 (258)

One-On-One with Dr. Rachel Levine

Patient Safety, 2019
Rachel Levine, MD, is secretary of health for the Commonwealth of Pennsylvania and a professor of pediatrics and psychiatry at Penn State. An accomplished authority on many topics, including adolescent health, eating disorders, and LGBTQ medicine, Dr ...
Susan Wallace
doaj   +2 more sources

Origins, development and outcomes of Public Private Partnerships in Ireland: the case of PPPs in social housing regeneration

, 2009
This paper explores the origins and development of PPPs in the delivery of public services and infrastructure internationally and in Ireland, where they were introduced on a pilot basis in June 1999.
Hearne, Rory Dr.
core  

Concerted Action of Targeted Nucleic Acid Therapeutics as Flexible, Precision and Personalized Cancer Treatment

Advanced Science, EarlyView.
Combinations of small activating RNAs and small interfering RNAs were developed as personalized precision therapies that simultaneously activate tumor suppressors and silence oncogenes according to the molecular signatures of patient tumors. This combination strategy demonstrated superior anticancer efficacy, highlighting the promise of precision ...
Jing Wu, Jiaxuan Chen, Abdechakour Elkihel, Wenjun Lan, Nicolas Fraunhoffer, Dandan Zhu, Baoping Lian, Christina Galanakou, Zhancun Bian, Xi Liu, Odile Gayet, Loic Moubri, Julie Aglietti Roques, Vikash Reebye, Nagy Habib, Xiaoxuan Liu, Nelson Dusetti, Juan Lucio Iovanna, Ling Peng   +18 more
wiley   +1 more source

Learning how to be an active citizen in Dublin’s Docklands: the significance of informal processes

, 2009
This study investigated how people learn active citizenship in Dublin’s Docklands. Informal (i.e. contextual and incidental) and non-formal (i.e. community education) learning was explored.
Breen, Marianne Dr., Rees, Nicholas Prof.   +1 more
core  

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

Advanced Science, EarlyView.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa, Hui Yuan, Jingui Ma, Zhigang Yang, Mei Wang, Weibiao Wang, Lingling Yang, Fen Ma, Weiman Zhang, Gidion Wilson Mening'oo, Guoning Chen, Xueqin Ma   +11 more
wiley   +1 more source

Investing in children: submission to the Minister for Social Community and Family Affairs on the 1999 Budget.

, 1988
The aIm of the Combat Poverty Agency is to work for the prevention and decrease of poverty and social exclusion and the reduction of inequality in ...
Combat Poverty Agency
core  

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

Maternal Exercise Rescues Embryonic Osteogenesis Impaired due to POLG Mutation Through a Potential Apelin‐ATF4 Axis

Advanced Science, EarlyView.
Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae, Ryan C. Riddle, Zhihua Jiang, Chaeyoung Shin, Min Du, Jun Seok Son   +5 more
wiley   +1 more source

THE EFFECT OF PRAZOSIN ON COMBAT RELATED POSTTRAUMATIC STRESS DISORDER NIGHTMARES

Journal of Research in Medical Sciences, 2003
Introduction: Several studies have shown noradrenergic system hyperactivity in posttraumatic stress disorder. Four Vietnam combat veterans with chronic PTSD, prescribed prazosin ?1 adrenergic receptor antagonist reported reduction or completely ...
G ASSADOUAHI, GH AHMADZADEH, J MAHMOUDI GHARAEI, N BASHARDOOST, T FAGHIHI   +4 more
doaj  

Endocrine dysfunction in the pathogenesis of combat surgical trauma and post-traumatic stress disorder (scientific review)

Медицина неотложных состояний
The modern hostilities have created the unique challenges for medical, surgical and rehabilitation assistance to people liable for military service who have sustained injuries in the battle conditions.
O.Yu. Usenko, I.P. Khomenko, A.E. Kovalenko, V.V. Nehoduiko, K.V. Misyura, A.V. Zabronsky   +5 more
doaj   +1 more source