The use of mono- and combination drug therapy in men and women with lower urinary tract symptoms (LUTS) in the UK: a retrospective observational study [PDF]
BMC Urology, 2021 Background Combination drug therapy for lower urinary tract symptoms (LUTS) is beneficial to selected patients and recommended by guidelines. Patterns of real-world LUTS drug use, especially combination drug therapy, have not been studied extensively ...
Mahmood Ali +6 more
doaj +4 more sources
HSA-based multi-target combination therapy: regulating drugs’ release from HSA and overcoming single drug resistance in a breast cancer model [PDF]
Drug Delivery, 2018 Multi-drug delivery systems, which may be promising solution to overcome obstacles, have limited the clinical success of multi-drug combination therapies to treat cancer.
Yi Gou +12 more
doaj +2 more sources
Emergence of prions selectively resistant to combination drug therapy. [PDF]
PLoS Pathogens, 2020 Prions are unorthodox infectious agents that replicate by templating misfolded conformations of a host-encoded glycoprotein, collectively termed PrPSc.
Cassandra M Burke +4 more
doaj +2 more sources
Customising the therapeutic response of signalling networks to promote antitumor responses by drug combinations [PDF]
Frontiers in Oncology, 2014 Drug resistance, de novo and acquired, pervades cellular signalling networks from one signalling motif to another as a result of cancer progression and/or drug intervention.
Alexey eGoltsov +4 more
doaj +7 more sources
Anti-Cholinesterase Combination Drug Therapy as a Potential Treatment for Alzheimer's Disease. [PDF]
Brain Sci, 2021 Amat-Ur-Rasool H +3 more
europepmc +3 more sources
Analysis of combination drug therapy to develop regimens with shortened duration of treatment for tuberculosis. [PDF]
PLoS One, 2014 Drusano GL +7 more
europepmc +3 more sources
Comparison of null models for combination drug therapy reveals Hand model as biochemically most plausible. [PDF]
Sci Rep, 2019 Sinzger M +3 more
europepmc +3 more sources
Omadacycline Potentiates Clarithromycin Activity Against Mycobacterium abscessus
Frontiers in Pharmacology, 2021 Mycobacterium abscessus is a difficult respiratory pathogen to treat, when compared to other nontuberculus mycobacteria (NTM), due to its drug resistance.
Bui Thi Bich Hanh +7 more
doaj +1 more source
Metabolic Derangements with Anticonvulsants in Children with Generalised Tonic-clonic Epilepsy: A Cross-sectional Study [PDF]
Journal of Clinical and Diagnostic Research, 2023 Introduction: Epilepsy is one of the most prevalent noncommunicable neurologic conditions, accounting for significant disability and mortality. The effects of Antiepileptic Drugs (AEDs) on total cholesterol, triglycerides, High-Density Lipoprotein ...
Jyoti Sharma +3 more
doaj +1 more source
Basic principles of combination therapy: focus on drug-drug interaction
Кардиоваскулярная терапия и профилактика, 2021 The article is devoted to the issue of drug interactions in the combination regimens. Today, when drug therapy is the first-line approach for patients with noncommunicable diseases, and the world population ageing leads to an increase in the number of ...
S. Yu. Martsevich +2 more
doaj +1 more source