Results 111 to 120 of about 1,434,198 (304)

The lag time in initiating clinical testing of new drugs in combination with radiation therapy, a significant barrier to progress? [PDF]

, 2014
Philip Blumenfeld, Raphael M. Pfeffer, Zvi Symon, Robert B. Den, Adam P. Dicker, David Raben, Yaacov Richard Lawrence   +6 more
openalex   +1 more source

Position Statement by Experts of the Polish Menopause and Andropause Society on menopausal hormone therapy with an oral combination drug containing oestradiol 1 mg and progesterone 100 mg [PDF]

, 2021
Małgorzata Bińkowska, Grzegorz Jakiel, Tomasz Paszkowski, Violetta Skrzypulec‐Plinta, Wojciech Zgliczyński   +4 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Comparing Triple Combination Drug Therapy and Traditional Monotherapy for Better Survival in Patients With High-Risk Hypertension: A Systematic Review. [PDF]

Cureus, 2023
Zaman MA, Awais N, Satnarine T, Ahmed A, Haq A, Patel D, Gutlapalli SD, Hernandez GN, Seffah K, Khan S.   +9 more
europepmc   +1 more source

Entry of the antipsychotic drug, olanzapine, into the developing rat brain in mono- and combination therapies

, 2022
Yifan Huang, Fiona Qiu, Mark D. Habgood, Shuai Nie, Katarzyna M. Dzięgielewska, Norman R. Saunders   +5 more
openalex   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Vitamin D and Metreleptin: A Therapeutic Alliance for Treating Depression Associated with Obesity [PDF]

Journal of Clinical and Diagnostic Research
Vitamin D has multifaceted roles in brain function beyond its traditional role in bone health, impacting neurotransmitters, inflammation, and mood-regulating brain areas where its receptors are present.
Priyanka Venkatapathappa, Achal Shetty, Ashakiran Srinivasaiah, Harish Rangareddy   +3 more
doaj   +1 more source

Medical use and combination drug therapy among US adult users of central nervous system stimulants: a cross-sectional analysis. [PDF]

BMJ Open, 2023
Moore TJ, Wirtz PW, Curran JN, Alexander GC.   +3 more
europepmc   +1 more source

Incidence of HIV-1 Drug Resistance Among Antiretroviral Treatment-Naive Individuals Starting Modern Therapy Combinations [PDF]

, 2017
By use of simulations we imputed human immunodeficiency virus type 1 drug resistance incidence to protease inhibitor-based or nonnucleoside reverse-transcriptase inhibitor-based combination therapy.
Battegay, Manuel, Bernasconi, Enos, Böni, Jürg, Cavassini, Matthias, Cellerai, Cristina, Furrer, Hansjakob, Günthard, Huldrych F., Hirschel, Bernard, Klimkait, Thomas, Ledergerber, Bruno, Shah, Cyril, Vernazza, Pietro L., von Wyl, Viktor, Yerly, Sabine   +13 more
core  

Combination Drug Therapy for Persistent Pulmonary Hypertension of the Newborn [PDF]

, 2017
Noritaka Yokoo, Chieko Marumo, Yoshinobu Nishida, Jun Iio, Shinji Maeda, Michiko Nonaka, Toshiro Maihara   +6 more
openalex   +1 more source