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Problems of Combination Drug Therapy in Children
Epilepsia, 1988Summary: Despite the current trend toward monotherapy, polytherapy in children with epilepsy is still common. A drug combination is advantageous only if it achieves a higher efficacy: toxicity ratio (therapeutic index) or if its antiepileptic spectrum is wider.
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Drug Combinations as Rational Antihypertensive Therapy
Archives of Internal Medicine, 1974The goal of antihypertensive therapy is to restore blood pressure to normal with as few side effects as possible. Usually this is best accomplished by skillfully combining two or more drugs in the regimen. A diuretic should be the cornerstone on which the regimen is built; for many patients with mild hypertension, a diuretic will be the only drug ...
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Combination drug therapy for dyslipidaemia
Current Opinion in Lipidology, 1993The use of combination therapy with lipid-lowering agents which have complementary effects on lipoprotein metabolism is an important option for the treatment of severe hyperlipoproteinaemia. This review presents a discussion of recent studies of combination therapy set against the background of existing knowledge in this important therapeutic area.
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Combined drug therapy of hypertension
1960Since current drug treatment of hypertension is primarily suppressive rather than curative, the prolonged maintenance of blood pressure reduction is as important as the ability to cause an early and marked depression of the blood pressure by acute treatment.
S. W. Hoobler, P. Lauwers
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Combination Drug Therapy for Hypercholesterolemia
Archives of Internal Medicine, 1993Background: The National Cholesterol Education Program recommends achievement of a defined target level of low-density lipoprotein cholesterol (LDL-C) for the treatment of hypercholesterolemia. They endorse the use of niacin and/or sequestrants as the first line of therapy to achieve such target LDL-C level.
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Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies
Ca-A Cancer Journal for Clinicians, 2022Paolo Tarantino +2 more
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Radiation therapy‐associated toxicity: Etiology, management, and prevention
Ca-A Cancer Journal for Clinicians, 2021Kyle Wang
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Combination Drug Therapy versus Single Drug Therapy
2nd Annual International Conference on Pharmacology and Pharmaceutical Sciences (PHARMA 2014), 2014Dr. Zaheda Bano +2 more
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