Results 51 to 60 of about 2,657,261 (342)
Nanomedicine-mediated Combination Drug Therapy in Tumor
, 2017 REVIEW ARTICLE Nanomedicine-Mediated Combination Drug Therapy in Tumor Dazhong Chen, Fangyuan Xie, Duxin Sun, Chuan Yin, Jie Gao and Yanqiang Zhong Department of Pharmaceutical Sciences, Second Military Medical University, 325 Guohe Road, Shanghai 200433,
Dazhong Chen +5 more
semanticscholar +1 more source
Advances in drug delivery system for platinum agents based combination therapy
Cancer Biology & Medicine, 2015 Platinum-based anticancer agents are widely used as first-line drugs in cancer chemotherapy for various solid tumors. However, great side effects and occurrence of resistance remain as the major drawbacks for almost all the platinum drugs developed.
Xiang Kang +5 more
doaj +1 more source
Optimized Treatment Schedules for Chronic Myeloid Leukemia
, 2016 Over the past decade, several targeted therapies (e.g. imatinib, dasatinib, nilotinib) have been developed to treat Chronic Myeloid Leukemia (CML). Despite an initial response to therapy, drug resistance remains a problem for some CML patients.
Dingli, David +4 more
core +3 more sources
Frontiers in Microbiology, 2021 Colistin is a last resort antibiotic against the critical status pathogen Pseudomonas aeruginosa. Virulence and related traits such as biofilm formation and serum resistance after exposure to sub-inhibitory levels of colistin have been underexplored.
Mumina Javed +14 more
doaj +1 more source
Co-targeting of DNA, RNA, and protein molecules provides optimal outcomes for treating osteosarcoma and pulmonary metastasis in spontaneous and experimental metastasis mouse models. [PDF]
, 2017 Metastasis is a major cause of mortality for cancer patients and remains as the greatest challenge in cancer therapy. Driven by multiple factors, metastasis may not be controlled by the inhibition of single target.
DeVere White, Ralph W +11 more
core +1 more source
Combination Cancer Therapy and Reference Models for Assessing Drug Synergy in Glioblastoma
Current OncologyGlioblastoma is currently an incurable disease despite the development of a wide variety of therapeutic approaches, from surgical methods to immunotherapy.
Semyon A. Sinyavskiy +4 more
doaj +1 more source
Exploiting evolution to treat drug resistance: Combination therapy and the double bind [PDF]
, 2011 Although many anti cancer therapies are successful in killing a large percentage of tumour cells when initially administered, the evolutionary dynamics underpinning tumour progression mean that often resistance is an inevitable outcome, allowing for new ...
Alexander R. A. Anderson +2 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar +8 more
wiley +1 more source
Revista Brasileira de Geriatria e Gerontologia, 2017 Objective: To evaluate the epidemiological, clinical and evolutionary aspects of tuberculosis in elderly patients of a university hospital in Belém, Pará.
Emanuele Cordeiro Chaves +4 more
doaj +2 more sources
Frontiers in Oncology, 2022 Lung cancer is a type of cancer with higher morbidity and mortality. In spite of the impressive response rates of nab-paclitaxel (nab-PTX) or programmed cell death-1 (PD-1) and its ligand inhibitors, the effective treatment remains limited.
Jun Zhang +5 more
doaj +1 more source