Results 91 to 100 of about 9,546,669 (393)
Nature Communications, 2017 Herein, an intelligent biodegradable hollow manganese dioxide (H-MnO2) nano-platform is developed for not only tumor microenvironment (TME)-specific imaging and on-demand drug release, but also modulation of hypoxic TME to enhance cancer therapy ...
Guangbao Yang +7 more
semanticscholar +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Optimized Treatment Schedules for Chronic Myeloid Leukemia
, 2016 Over the past decade, several targeted therapies (e.g. imatinib, dasatinib, nilotinib) have been developed to treat Chronic Myeloid Leukemia (CML). Despite an initial response to therapy, drug resistance remains a problem for some CML patients.
Dingli, David +4 more
core +3 more sources
Expert Review of Anti-Infective Therapy, 2019 Introduction: Anti-Microbial Resistance (AMR) is a pandemic which threatens modern medicine. There is a lack of effective drug treatment due to the slow pace, high cost and low achievable sales prices of new antibiotic monotherapies.
A. Coates, Yanmin Hu, James Holt, P. Yeh
semanticscholar +1 more source
FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source
Azilsartan/chlorthalidone combination therapy for blood pressure control
Integrated Blood Pressure Control, 2013 Judy WM ChengMassachusetts College of Pharmacy and Health Sciences, Brigham and Women's Hospital, Boston, MA, USABackground: Edarbyclor® is a combined angiotensin receptor blocker (ARB) and thiazide-like diuretic (azilsartan and chlorthalidone ...
Cheng JW
doaj
An Overlap Analysis of Occupational Therapy Electronic Journals Available in Full-Text Databases and Subscription Services [PDF]
, 2008 In order to convert occupational therapy journal subscriptions from print to electronic, a university library, in collaboration with its Occupational Therapy Program, compared full-text databases and journal subscription services.
Schroeder, Judy
core +3 more sources
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Vascular Health and Risk Management, 2012 Peter P Toth1, Kamlesh M Thakker2, Ping Jiang2, Robert J Padley21University of Illinois College of Medicine, Peoria, and CGH Medical Center, Sterling, 2Abbott, Abbott Park, IL, USABackground: The purpose of this research was to compare the effects of ...
Toth PP, Thakker KM, Jiang P, Padley RJ
doaj
A recently developed approach in tumor therapy using Salmonella
BioTechnologia, 2020 There are three main approaches in cancer treatment: surgery, chemotherapy, and radiotherapy. Recently, the use of bioengineered bacteria as therapeutic agents has been shown to have some valuable properties in the treatment of cancer, which do not exist
MAHMOUD GHARBAVI +4 more
doaj +1 more source