Results 151 to 160 of about 1,454,174 (267)

Add-on combination therapy with monoclonal antibodies: Implications for drug development. [PDF]

J Prev Alzheimers Dis
Cummings J, Burstein AH, Fillit H.
europepmc   +1 more source

Clinical Efficacy and Safety of Naltrexone Combination Therapy in Older Patients with Severe Pruritus [PDF]

, 2016
Jungsoo Lee, Jung U Shin, Seongmin Noh, Chang Ook Park, Kwang Hoon Lee   +4 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Clinical and demographic characteristics of patients with hormone-sensitive HER2-negative advanced breast cancer receiving ribociclib in combination with endocrine therapy or combination chemotherapy in routine clinical practice in the Russian Federation: interim results of the ValerEE study

Lyudmila Zhukova, Е. В. Артамонова, Liubov Yu Vladimirova, T. V. Vinogradova, L. M. Voronkova, R. S. Zhikhorev, N. V. Leushina, Oleg Mironov, Violetta Reznikov, E. V. Semenov   +9 more
openalex   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Ameliorative effects of combination therapy with metformin and crocin in experimental colitis in rats. [PDF]

Res Pharm Sci
Koohshekan B, Minaiyan M, Hashemnia M, Aarabi MH.   +3 more
europepmc   +1 more source

A Case of Vogt-Koyanagi-Harada-like Syndrome Following Nivolumab and Ipilimumab Combination Therapy in a Patient with Malignant Pleural Mesothelioma: Case Report

Jae Rock, Dong Ho Park, Yong Koo Kang
openalex   +2 more sources

Rituximab Monotherapy versus Rituximab and Bortezomib Combination Therapy for Treatment of Non-paraneoplastic Autoimmune Retinopathy

, 2022
Arash Maleki, Amanda Colombo, Sydney Look-Why, Peter Y. Chang, Stephen D. Anesi, C. Stephen Foster   +5 more
openalex   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Clinical efficacy and psychological benefits of combination therapy in elderly patients with hypertension. [PDF]

Am J Transl Res
Zhang P, Cui T, Ye X, Lu M.
europepmc   +1 more source