Results 201 to 210 of about 1,454,174 (267)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Strain diversity drives heterogeneous responses to tuberculosis combination therapy

Yoon MH, Culviner PH, Moraes MP, Nitta H, Thuong NTT, Fortune SM, Aldridge BB.   +6 more
europepmc   +1 more source

Intratumoral microbiota-derived S1P sensitizes the combination therapy of capecitabine and PD-1 inhibitors. [PDF]

iScience
Dai CS, Qi TT, Shang HL, Xie RH, Liu H, Liu ZM, Cui YM, Zhang YH.   +7 more
europepmc   +1 more source

Developing Oxaliplatin and Il-15 Co-Carried Gels as Drug Depots to Enable Triple-Interlocked Combination Therapy for Colorectal Cancer

Dandan Jiang, Haiqian Nie, Ziang Wang, Yuhan Xiong, Huimin Shen, Ya Gao, Xiali Zhu, Zhenkun Mao   +7 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Safety and efficacy of relugolix combination therapy in symptomatic uterine fibroids. [PDF]

Facts Views Vis Obgyn
De Angelis MC, Ambrosetti F, Reppuccia S, Nardelli F, Zizolfi B, Mercurio A, Maiorana A, Di Spiezio Sardo A.   +7 more
europepmc   +1 more source

CASE STUDY THE EFFECT OF COMBINATION OF BABY MASSAGE AND LULLABY MUSIC THERAPY ON BABY SLEEP QUALITY

Muhammad Romadhon, Wahyudi Mulyaningrat, Annas Sumeru   +2 more
openalex   +2 more sources

Effectiveness of cervical cancer therapy using neoadjuvant chemotherapy in combination with radical surgery: a meta-analysis

, 2017
Yijie Fu, Tianmin Zhu, Hui Li
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Azelastine-Fluticasone Combination Therapy in Allergic Rhinitis: Current Evidence and Clinical Implications in Children and Adults. [PDF]

Pharmaceuticals (Basel)
Indolfi C, Klain A, Dinardo G, Grella C, Di Filippo P, Fatica I, Napolano V, Decimo F, Miraglia Del Giudice M.   +8 more
europepmc   +1 more source