Results 241 to 250 of about 9,546,669 (393)
Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim +18 morewiley +1 more sourceSimultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan +8 morewiley +1 more sourceTumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick +6 morewiley +1 more sourceVedolizumab-steroid combination therapy improves long-term prognosis in patients with ulcerative colitis. [PDF]
BMC GastroenterolYamada Y, Ishida N, Takebe T, Takahashi K, Asai Y, Tamura S, Matsuura T, Takano R, Matsuura A, Yamade M, Iwaizumi M, Hamaya Y, Yamada T, Osawa S, Yoshizawa Y, Hosoda Y, Ota Y, Hanai H, Sugimoto K. +18 moreeuropepmc +1 more sourceCombination antiretroviral therapy and the risk of myocardial infarction [PDF]
, 2003 Abbadesse, V, Abrams, DI, Abrescia, N, Akerlund, B, Alberici, F, Alessandrini, A, Anderson, J, Antinori, A, Antinori, A, Antunes, F, Arduino, R, Arici, C, Arici, C, Arlotti, M, Austin, D, Baker, B, Bal, J, Balestre, E, Ballardini, G, Banhegyi, D, Barton, S, Bartsch, G, Bartsch, G, Baxter, J, Bedini, A, Ben-Ishai, Z, Benfield, T, Beniowski, M, Bentwich, Z, Bentz, L, Bernard, E, Bernard, N, Bernasconi, E, Beylot, C, Beylot, J, Beylot, J, Bezian, JH, Bieckel, M, Blaizeau, MJ, Blaxhult, A, Blok, W, Bonarek, M, Bonasso, M, Bonnet, F, Borleffs, J, Boron-Kaczmarska, A, Bottari, G, Boulant, B, Brettle, R, Brevenboer, B, Brinkman, K, Bronsveld, W, Bruno, R, Bruun, J, Bucher, H, Burgisser, P, Cadafalch, J, Cadeo, G, Caggese, L, Caissotti, C, Calvo, G, Calvo, G, Calvo, G, Caramello, P, Cargnel, A, Carnevale, G, Carosi, G, Carr, A, Castelli, F, Castera, L, Cattacin, S, Chaillou, S, Chambon, D, Chene, G, Chiesi, A, Chiodo, F, Chiriann, A, Chirianni, A, Chossat, I, Chuah, J, Cioppi, A, Cipriano, C, Cipriano, G, Claessen, F, Clotet, B, Clumeck, N, Clumeck, N, Coadou, B, Codina, C, Cohn, D, Colangeli, V, Colebunders, R, Colomba, A, Conejero, J, Conri, C, Constans, J, Cooper, D, Coronado, O, Couzigou, P, Crane, LR, D'Alessandro, M, Dabis, F, Dabis, F, Danner, S, De La Taille, C, De Lalla, F, De Longis, P, De Luca, A, De Marco, M, de Marie, S, De Salvador-Guillouet, F, De Stefano, C, De Wit, S, De Wit, S, De Wit, S, de Wolf, F, Decoin, M, Del Cacho, E, Dellamonica, P, Delveaux, S, Diaz, B, Dietrich, M, Djossou, F, Domingo, P, Doutre, MS, Dupon, M, Dupon, M, Durant, J, Dutoit, D, Dutronc, H, Egger, M, El-Sadr, WM, El-Sadr, WM, El-Sadr, WM, Erb, P, Esposito, R, Esposito, R, Fankhauser, W, Faure, I, Ferrara, S, Ferraro, T, Fierz, W, Filandras, A, Filice, G, Finazzi, R, Fischer, M, Fisher, E, Fisher, M, Flamholc, L, Flepp, M, Fleury, H, Fontana, A, Fontas, E, Fontas, E, Formaggio, AM, Franci, P, Francioli, P, Francioli, P, Friedland, G, Friis-Moller, N, Friis-Moller, N, Frissen, P, Furrer, H, Furrer, HJ, Fuster, M, Gabbuti, A, Galloni, D, Galperine, T, Garcia-Benayas, T, Gargalianos, P, Gasiorowski, J, Gatell, J, Gatell, JM, Gelie, P, Gennero, L, Gerard, M, Gerstoft, J, Ghinelli, F, Godfried, M, Goebel, FD, Gonzalez-Lahoz, J, Gordin, F, Gorgievski, M, Gowers, A, Grima, P, Grisorio, B, Guttman, R, Gyssens, I, Hakangard, C, Hammer, S, Heidemann, B, Hemmer, R, Heripret, L, Hermans, P, Hildebrand, M, Hillbrand, M, Hirschel, B, Hirschel, B, Hoepelman, I, Horban, A, Houyez, F, Jacqmin-Gadda, H, Jaspers, C, Jaubert, D, Jeurissen, F, Johnson, AM, Johnson, MA, Jou, A, Juttmann, J, Kabeya, K, Kaiser, L, Karlsson, A, Karydis, I, Katlama, C, Katzenstein, T, Kauffmann, R, Keuter, M, Kind, C, Kirk, O, Kirk, O, Kirk, O, Kjaer, J, Klimkait, T, Knysz, B, Koger, E, Konopnicki, D, Koopmans, P, Koppel, K, Kosmidis, J, Kroon, F, Krum, E, Krum, E, La Gala, A, Labarerre, S, Lacoste, D, Lacut, JY, Lafarie, S, Lafarie, S, Lafon, ME, Lange, J, Lauper, U, Lavignolle, V, Lavignolle, V, Law, G, Law, M, Law, MG, Law, MG, Lawson-Ayayi, S, Lazzarin, A, Lazzarin, A, Le Bras, M, Le Bras, M, Ledergerber, B, Ledergerber, B, Leemhuis, M, Leng, B, Lichtner, M, Lo Caputo, S, Loeliger, E, Loiacono, L, Loveday, C, Lowe, S, Lundgren, JD, Lundgren, JD, Lundgren, JD, Lundgren, JD, Luskin-Hawk, R, Maayan, S, Machala, L, Maeland, A, Magnani, G, Mallal, S, Malvy, D, Manconi, PE, Mancuso, S, Manegold, C, Mannazzu, M, Mansinho, K, Markowitz, N, Martin-Carbonero, L, Martinelli, C, Masquelier, B, Mateau, S, Matute, A, Mazzotta, F, Mazzotta, F, McFarlane, R, Meenhorst, P, Meester, R, Meester, R, Menichetti, F, Mercey, D, Merchadou, L, Mercie, P, Merli, S, Mestre, C, Migliorino, G, Mijch, A, Miller, V, Minafra, G, Miro, JM, Mocroft, A, Moioli, C, Mondain-Miton, V, Monforte, AD, Monforte, AD, Monforte, AD, Monforte, VO, Monteforte, AD, Montesarchio, E, Montroni, M, Moreau, F, Moreau, JF, Morfeldt, L, Morfeldt, L, Morfeldt, L, Morlat, P, Moroni, M, Mulcahy, F, Mulder, J, Mura, MS, Mushatt, D, Mussini, C, Nappa, S, Narciso, P, Narciso, P, Nasti, G, Neaton, J, Neaton, J, Neau, D, Nellen, F, Nielsen, J, Noto, P, Nouts, C, Novati, R, Ochoa, A, Opravil, M, Ormaasen, V, Ortolani, P, Ortona, L, Paccaud, F, Pagano, G, Palmer, G, Panos, G, Pantaleo, G, Parkin, J, Pasquinucci, S, Pastecchia, C, Pastore, G, Payen, MC, Pedersen, C, Pehrson, P, Pellegrin, I, Pellegrin, JL, Pellegrin, JL, Perbost, I, Perdios, J, Pereira, F, Perenboom, R, Perez, G, Perrin, L, Petoumenos, K, Petoumenos, K, Petrelli, E, Petrosillo, N, Pezzotti, P, Pezzotti, P, Phillips, AN, Phillips, AN, Phillips, AN, Piano, P, Piazza, M, Piersantelli, N, Piffaretti, JC, Pinching, A, Piscopo, R, Pivetaud, JP, Pizzigallo, E, Pnyka, M, Pogany, K, Poggio, A, Poll, B, Poll, B, Pollack, S, Pradier, C, Pradier, C, Pradier, C, Pradier, C, Prestileo, T, Prins, J, Pristera, R, Proenca, R, Prokopowicz, D, Prouvost-Keller, B, Pugliese, P, Pusterla, L, Ragnaud, JM, Ragnaud, JM, Rahelinirina, V, Raise, E, Reiss, P, Reiss, P, Reiss, P, Reiss, R, Rhiebaut, R, Richter, C, Rickenbach, M, Rickenbach, M, Rispal, P, Rizzardini, G, Rockstroh, J, Roge, B, Roger, PM, Roth, N, Rudin, C, Ruggieri, A, Ruys, T, Sabin, CA, Sabin, CA, Saint-Marc, T, Salamon, R, Salcuni, P, Salzberger, B, Sambatakou, H, Sambeat, MA, Sampson, J, Santopadre, P, Santoro, D, Sawitz, A, Scasso, A, Scerbo, A, Schattenkerk, JKE, Schieveld, S, Schippers, E, Schneider, M, Schrey, G, Schupbach, J, Schurink, C, Sciandra, M, Scullard, G, Series, C, Sighinolfi, L, Sinicco, A, Sirera, G, Sjol, A, Sjol, A, Skett, J, Skinhoj, P, Soranzo, ML, Soravia-Dunand, V, Soriano, V, Soscia, F, Speck, R, Sprenger, HG, Staszewski, S, Staub, T, Sundstrom, A, Sunstrom, A, Suter, F, Tacconi, L, Taupin, JL, Taytard, A, Tchamgoue, S, Tedaldi, E, Telenti, A, Telenti, A, Telgt, D, Telzak, E, ten Kate, RW, ten Napel, C, ten Veen, J, Thiebaut, R, Thompson, G, Thulin, G, Tirelli, U, Torres, F, Torres, F, Tositti, G, Touchard, D, Tressler, R, Trimoulet, P, Trkola, A, Trocha, H, Tundo, P, Tural, C, Turner, D, Ursitti, M, Uwamaliya, B, van Dam, P, van der Ende, M, van der Geest, S, van der Heul, C, van der Meer, J, van der Poll, T, van der Valk, M, van der Ven, A, van der Ven, E, van Eeden, A, van Gorp, E, Van Laethem, Y, van Leusen, R, van Lunzen, J, Van Valkengoed, L, Vandenbos, F, Vangi, D, Vanhems, P, Vaque, A, Vella, S, Verbon, A, Vernazza, P, Vetter, N, Viallard, JF, Viard, JP, Vigevani, GM, Vimard, E, Vincenti, A, Vriesendorp, R, Vullo, V, Vullo, V, Watson, K, Weber, J, Weber, R, Weber, R, Weber, R, Weber, R, Weigel, H, Weller, I, Wentworth, D, Wit, F, Wood, H, Yerly, S, Yust, I, Zaccarelli, M, Zaheri, S, Zauli, T, Zoli, A +535 morecore
