A Case of EGFR-mutant Squamous Cell Lung Cancer Treated With Necitumumab Combination Therapy. [PDF]
Inomata M+6 more
europepmc +1 more source
Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski+13 more
wiley +1 more source
Case report: late adverse reactions in an epilepsy patient on combination therapy with valproate and lamotrigine. [PDF]
Sang H+4 more
europepmc +1 more source
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji+3 more
wiley +1 more source
Combination therapy with fosfomycin for <i>Staphylococcus aureus</i> bacteraemia or endocarditis: a systematic review and meta-analysis of randomized trials. [PDF]
Mourad A+4 more
europepmc +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
Impact of health education intervention on the patients' adherence to malaria artemisinin-based combination therapy in Kamuli District, Uganda. [PDF]
Bawate C+3 more
europepmc +1 more source