Results 41 to 50 of about 46,397 (267)
Solving generic nonarchimedean semidefinite programs using stochastic game algorithms
, 2016 A general issue in computational optimization is to develop combinatorial algorithms for semidefinite programming. We address this issue when the base field is nonarchimedean.
Blekherman G. +5 more
core +6 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Cost-sharing in Parking Games [PDF]
Discrete Mathematics & Theoretical Computer ScienceIn this paper, we study the total displacement statistic of parking functions from the perspective of cooperative game theory. We introduce parking games, which are coalitional cost-sharing games in characteristic function form derived from the total ...
Jennifer Elder +3 more
doaj +1 more source
Larger Corner-Free Sets from Better NOF Exactly-$N$ Protocols
Discrete Analysis, 2021 Larger corner-free sets from better NOF exactly-$N$ protocols, Discrete Analysis 2021:19, 9 pp. If $G$ is an Abelian group, then a _corner_ in $G^2$ is a subset of the form $\{(x,y),(x+d,y),(x,y+d)\}$ with $d\ne 0$.
Nati Linial, Adi Shraibman
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Two games on arithmetic functions: SALIQUANT and NONTOTIENT [PDF]
Discrete Mathematics Letters, 2023 Paul Ellis +3 more
doaj +1 more source
Annales de Didactique et de Sciences CognitivesThis article offers a didactic analysis of an activity derived from scientific outreach, at the interface between mathematics and computer science. We analyse an activity based on a particular combinatorial game and a machine which learns to win at this ...
Pierre Esclafit, Simon Modeste
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source