Results 51 to 60 of about 196,827 (283)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Spiders for rank 2 Lie algebras
A spider is an axiomatization of the representation theory of a group, quantum group, Lie algebra, or other group or group-like object. We define certain combinatorial spiders by generators and relations that are isomorphic to the representation theories
A.A. Kirillov +13 more
core +2 more sources
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
We present an independently discovered Andrews–Curtis trivialization of the balanced trivial group presentation MS9(w∗)=〈a,b∣a−1b9ab−10,a−1b−1aba−1〉 obtained through automated theorem proving.
Alexei Lisitsa
doaj +1 more source
Structural Synthesis of 3-DoF Spatial Fully Parallel Manipulators
In this paper, the architectures of three degrees of freedom (3-DoF) spatial, fully parallel manipulators (PMs), whose limbs are structurally identical, are obtained systematically.
Alfonso Hernandez +3 more
doaj +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Stable Andrews-Curtis trivialization of AK(3) revisited. A case study using automated deduction
Recent work by Shehper et al. (2024) [13] proposed that the well-known Akbulut–Kirby presentation AK(3) is stably Andrews–Curtis (AC) equivalent to the trivial presentation, based on a reduction to a previously studied presentation P.
Alexei Lisitsa
doaj +1 more source
On problems concerning fixed-point-free permutations and on the polycirculant conjecture-a survey [PDF]
Fixed-point-free permutations, also known as derangements, have been studied for centuries. In particular, depending on their applications, derangements of prime-power order and of prime order have always played a crucial role in a variety of ...
Majid Arezoomand +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
New Andrews–Curtis trivializations for Miller–Schupp group presentations
We present recent developments in the applications of automated theorem proving in the investigation of the Andrews–Curtis conjecture. We demonstrate previously unknown trivializations of group presentations from a parametric family MSn(w∗) of trivial ...
Alexei Lisitsa
doaj +1 more source

