Results 161 to 170 of about 9,522 (300)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

The RNA-First Fallacy: Conflating Evolutionary Ancestry with Prebiotic Primacy. [PDF]

Life (Basel)
Kahana A.
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

A MacMahon analysis view of cylindric partitions. [PDF]

Ramanujan J
Li R, Uncu AK.
europepmc   +1 more source

Some combinatorial identities.

MATHEMATICA SCANDINAVICA, 1978
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Combinatorial identities by way of Wilf's multigraph model

International Journal of Mathematics and Mathematical Sciences, 2006
Theresa L. Friedman, Paul Klingsberg
doaj   +1 more source

Spatially tunable multiomic sequencing using light-driven combinatorial barcoding of molecules in tissues. [PDF]

Proc Natl Acad Sci U S A
Battistoni G, Torres-Garcia S, Sia CY, Corriero S, Boquetale C, Williams E, Cregeen A, Wasilewska K, Alini M, Hemmer N, IMAXT Cancer Grand Challenge Consortium, Balasubramanian S, Nicholson BC, Hannon GJ, Bressan D.   +14 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Imaging-Based Spatial Transcriptomics: Data Interpretation Methods and Biomedical Applications. [PDF]

Biology (Basel)
Li W, Zhou Y.
europepmc   +1 more source