Results 61 to 70 of about 6,800,360 (294)
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Domination analysis of combinatorial optimization problems
Discrete Applied Mathematics, 2003 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Gregory Z. Gutin +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
Iterative quantum algorithm for combinatorial optimization based on quantum gradient descent
Results in PhysicsCombinatorial optimization has wide and high-value applications in many fields of science and industry, but solving general combinatorial optimization problems is non-deterministic polynomial time (NP) hard.
Xin Yi +5 more
doaj +1 more source
Dominance rules in combinatorial optimization problems [PDF]
European Journal of Operational Research, 2011 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jouglet, Antoine, Carlier, Jacques
openaire +4 more sources
kyspencer/Survey-on-Nuclear-Combinatorial-Optimization-Studies: v1.0
, 2018 <p>This survey was conducted to determine which optimization algorithms nuclear engineers have used to solve combinatorial problems.</p ...
Kristy Yancey Spencer
core +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
OPTIMIZATION FOR ONE CLASS OF COMBINATORIAL PROBLEMS UNDER UNCERTAINTY
Adaptivni Sistemi Avtomatičnogo Upravlinnâ, 2019 We formalize uncertainty and compromise solution concepts, compromise criteria and conditions for a sufficiently common class of combinatorial optimization problems which functional contains a linear convolution of weights and of arbitrary numerical ...
A. A. Pavlov
doaj +1 more source
Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
FEBS Open Bio, EarlyView.The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source
Differential evolution for permutation-based combinatorial problems
, 2012 The chapter clarifies the differences between wide-sense combinatorial optimization and strict-sense combinatorial optimization and then presents a number of combinatorial problems encountered in practice.
Davendra, Donald David +3 more
core +1 more source