Results 101 to 110 of about 972,996 (315)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
, 1997 4 x 6 photograph, combine in a field, a water tower is in the backgroundH2010-041 Vanishing Early Scenes Vernell Johnson Coll. Churches, Old County Farms, Houses, Vanishing Country Scene Box 1 5607A[stamp] No.
Johnson, Vernell
core
EnergiesThe BN-350 is the first industrial fast neutron reactor in the history of nuclear energy. It is currently undergoing decommissioning. One of the key challenges of decommissioning is managing the solid radioactive waste that has accumulated throughout the
Nurzhan Mukhamedov +6 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
ASSOCIATION OF AGE WITH HEARING REHABILITATION AFTER COCHLEAR IMPLANT
Pakistan Armed Forces Medical Journal, 2020 Objective: To determine the hearing outcomes following unilateral cochlear implantation & speech therapy in patients with bilateral severe to profound sensorineural hearing loss. Study Design: Prospective observational study.
Fizza Naeem +3 more
doaj
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The Split-Apply-Combine Strategy for Data Analysis
Many data analysis problems involve the application of a split-apply-combine strategy, where you break up a big problem into manageable pieces, operate on each piece independently and then put all the pieces back together.
Hadley Wickham
core
Механика машин, механизмов и материаловThe paper examines aerodynamic modeling of air flows in the cleaning system of a combine harvester. A methodology has been developed for modeling the cleaning system, taking into account the movement of its elements, such as screens and boards, using the
Aliaksandr А. Kalinouski
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source