Results 11 to 20 of about 41 (40)
This comprehensive review elucidates the transformative role of the human microbiome in cancer biology, revealing innovative mechanistic insights into the intricate tumor–microbe interactions across diverse organ systems. This work highlights the clinical and translational value of novel microbiome‐based biomarkers for early detection, prognosis, and ...
Anqi Lin +50 more
wiley +1 more source
ABSTRACT Background and Aim Long‐term nucleos(t)ide analog (NUC) therapy is essential for chronic hepatitis B (CHB) management. However, data on long‐term outcomes, particularly for patients switching to tenofovir alafenamide (TAF) and patients with chronic kidney disease (CKD), remain limited.
Eiichi Ogawa +19 more
wiley +1 more source
Creating Biomimetic Bouligand Architectures for Biomedical and Healthcare Applications
Hierarchical Bouligand structures, evolved in nature for mechanical/functional advantages, are now replicated via various of strategies, including self‐assembly, biomimetic mineralization, shear brushing, electrostatic spinning, 3D printing, etc. Engineered architectures enable breakthroughs in bone regeneration, tooth repair, body protection, and ...
Hongye Yang +5 more
wiley +1 more source
Christian Bohr. Discoverer of Homotropic and Heterotopic Allostery
ABSTRACT This essay recounts and revisits the scientific contributions of Christian Bohr, highlighting his pivotal role in discovering allostery about 120 years ago. Bohr's meticulous experimentation led to identifying two distinct forms of allostery: homotropic (single‐ligand) and heterotropic (multi‐ligand), the latter widely recognized as the Bohr ...
Niels Bindslev
wiley +1 more source
ABSTRACT Ostracism (feeling ignored and excluded) triggers psychophysiological responses associated with distress. We investigated different coping responses after ostracism and explored whether these were preceded by unique facial thermal signatures, reflecting autonomic nervous system (ANS) activity. Using thermal infrared imaging, we recorded facial
Anneloes Kip +2 more
wiley +1 more source
Abstract Objectives To compare the efficacy and safety of sedation with midazolam and remimazolam for colorectal endoscopy. Methods This single‐center, two‐arm, post‐hoc analysis of the REM‐IICTJP01 study investigated the efficacy and safety of remimazolam for gastrointestinal endoscopic sedation.
Kanako Ogura +12 more
wiley +1 more source
Abstract Objectives In gastroenterology, sedation demand is increasing, although elderly patients are more prone to experiencing adverse events. Remimazolam, a novel ultra‐short‐acting benzodiazepine, may reduce recovery time after endoscopic procedures. Methods This study was a secondary analysis of the investigator‐initiated trial, which investigated
Ryoji Ichijima +11 more
wiley +1 more source
Elotuzumab‐mediated ADCC with Th1‐like Vγ9Vδ2 T cells to disrupt myeloma–osteoclast interaction
Signaling lymphocytic activation molecule family 7 (SLAMF7), an important therapeutic target of myeloma cells, is highly expressed in osteoclasts. Ex vivo‐expanded human Vγ9Vδ2 T cells are able to efficaciously exert antibody‐dependent cellular cytotoxicity (ADCC) with the anti‐SLAMF7 monoclonal antibody elotuzumab for SLAMF7‐expressing myeloma cells ...
Yusuke Inoue +19 more
wiley +1 more source
UEG Week 2025 Oral Presentations
United European Gastroenterology Journal, Volume 13, Issue S8, Page S7-S188, October 2025.
wiley +1 more source

