Results 111 to 120 of about 9,059,750 (314)

Working-fluid selection and thermoeconomic optimisation of a combined cycle cogeneration dual-loop organic Rankine cycle (ORC) system for solid oxide fuel cell (SOFC) waste-heat recovery

, 2020
M. Emadi, Nazanin Chitgar, O. A. Oyewunmi, C. Markides   +3 more
semanticscholar   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Multi-Objective Thermo-Economic Optimization of a Combined Organic Rankine Cycle (ORC) System Based on Waste Heat of Dual Fuel Marine Engine and LNG Cold Energy Recovery [PDF]

, 2020
Zhen Tian, Yingying Yue, Yuan Zhang, Bo Gu, Wenzhong Gao   +4 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Improved Coordinated Control Strategy for Auxiliary Frequency Regulation of Gas-Steam Combined Cycle Units

Energies
With the increasing penetration of renewable energy, the frequency regulation burden on thermal power units is growing significantly. Among them, combined cycle gas turbine (CCGT) units are playing an increasingly important role in grid ancillary ...
Zunmin Hu, Yilin Zhang, Tianhai Zhang, Xinyu Xiao, Li Sun, Lei Pan   +5 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Cost versus environment? Combined life cycle, techno‐economic, and circularity assessment of silicon‐ and perovskite‐based photovoltaic systems [PDF]

, 2023
Neill Bartie, Yazmín Lucero Cobos‐Becerra, Florian Mathies, Janardan Dagar, Eva Unger, Magnus Fröhling, Markus A. Reuter, Rutger Schlatmann   +7 more
openalex   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Investigation of a Hybridized Cascade Trigeneration Cycle Combined with a District Heating and Air Conditioning System Using Vapour Absorption Refrigeration Cooling: Energy and Exergy Assessments

Energies
The insufficiency of energy supply and availability remains a significant global energy challenge. This work proposes a novel approach to addressing global energy challenges by testing the supercritical property and conversion of low-temperature thermal ...
Larry Orobome Agberegha, Peter Alenoghena Aigba, Solomon Chuka Nwigbo, Francis Onoroh, Olusegun David Samuel, Tanko Bako, Oguzhan Der, Ali Ercetin, Ramazan Sener   +8 more
doaj   +1 more source