Results 231 to 240 of about 9,059,750 (314)

Radiotherapy dose may not affect prognosis in ESCC patients receiving first-line chemoradiotherapy-immunotherapy: A multicenter retrospective study. [PDF]

Cancer Immunol Immunother
Wen J, Liu X, Xu Y, Lin Z, Hou M, Gui Y, Cao J, Hou Q, Lv J, Wang L, Zhou W, Zeng Z, Shen W.   +12 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Mitochondrial dysfunction and apoptotic signaling induced by the combined action of 2-aminoethyl dihydrogen phosphate and methyl-β-cyclodextrin in melanoma cells. [PDF]

Front Pharmacol
Duarte de Oliveira TA, Nascimento Ribeiro RS, Nogueira Laiso RA, Alves MG, Moreira Sousa YE, Teles Pacheco de Matos ÍG, da Conceição Rabelo D, Grassi Rici RE, Chammas SM, Afeche SC, Doná Rodrigues Almeida GH, Maria DA.   +11 more
europepmc   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Synergistic roles of follicle-stimulating hormone and testosterone in Sertoli cell proliferation and testicular function in roosters. [PDF]

Poult Sci
Guo H, Deng X, Guo B, Li Z, Jin W, Li W, Kang X, Sun G.   +7 more
europepmc   +1 more source

A Mathematical Model of Nam Phong Combined Cycle Power Plant

, 2013
Mr.Khanchai Siriruchatapong, Dr.Boonsrang Direcksataporn, Dr.Somnuk Theerakulpisut   +2 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Dual Hedgehog/GLI1 and PI3K/Akt/mTOR Targeting Possesses Higher Efficacy to Inhibit T-Cell Acute Lymphoblastic Leukemia Growth. [PDF]

Cells
De Chiara M, Sicurella M, Melloni M, Conti I, Neri LM.   +4 more
europepmc   +1 more source

Stress intensity factor – Life: Improving high cycle fatigue understanding of laser powder bed fusion 316L stainless steel by combining effects of stress, defect size, and defect shape

Edwin B. Glaubitz, Orion Kafka, Nik Hrabe, Joy Gockel   +3 more
openalex   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source