Results 261 to 270 of about 10,899,248 (403)

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Comparison of efficacy and safety in two versus three cycles of neoadjuvant immunotherapy plus chemotherapy for esophageal squamous cell carcinoma. [PDF]

J Cardiothorac Surg
Ye G, Pan G, Zhu X, Liu H, Geng G, Jiang J.   +5 more
europepmc   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

PIK75 effectively reverses PI3K‒AKT activation caused by palbociclib resistance and synergistically inhibits the progression of esophageal squamous cell carcinoma. [PDF]

Sci Rep
Zhao Y, Li L, Jiang Y, Sun Y, Xu Y, Ye X, Zhang F, Zhu F, Pan Y, Ma S.   +9 more
europepmc   +1 more source

Integrated solar thermal combined cycle for power generation in Iraq

, 2019
Khalidah Al-Qayim
openalex   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Apigenin combined with cisplatin suppressed the progression of colorectal cancer by targeting the KRT23/Wnt/β-catenin signaling pathway. [PDF]

Discov Oncol
Dong L, Yang F, Wang X, Zhang W, Song J, Jiao P, Kang M, Guo Q, Si L, Zhang S, Huang M, Luo L, Li Y, Gong Y.   +13 more
europepmc   +1 more source

The Optimum Performance of the Combined Cycle Power Plant: A Comprehensive Review

, 2017
T. Ibrahim, Mohammed K. Mohammed, Omar I. Awad, M. Rahman, G. Najafi, F. Basrawi, A. N. A. Alla, R. Mamat   +7 more
semanticscholar   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Does Folcisteine (NATCA) Play a Role in Facilitating Seed Germination, Root Development, and Elevating Root AsA-GSH Cycle Efficiency Under Combined Copper-Cadmium Stress in Maize? [PDF]

Int J Mol Sci
Dong L, Zhao M, Hou K, Wei J, Liu Z, Wang R, Zhou Y, Gu W.   +7 more
europepmc   +1 more source