Results 31 to 40 of about 179,028 (261)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Optimum Electric Boiler Capacity Configuration in a Regional Power Grid for a Wind Power Accommodation Scenario

open access: yesEnergies, 2016
Wind power generation reduces our reliance on fossil fuels and can thus reduce environmental pollution. However, rapid wind power development has caused various issues related to power grid restructuring.
Da Liu   +3 more
doaj   +1 more source

Decision Making Control Algorithm for Cogeneration Plants in Operating with the Heat Accumulator Deep Analysis Model

open access: yesComplex Systems Informatics and Modeling Quarterly, 2022
Accurate production planning in both the short and long term is very important in cogeneration plants. Especially if the cogeneration unit operates under free electricity market conditions, which complicates the decision-making process as an additional ...
Varis Žentiņš   +3 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Method of statistical data processing safety ecological monitoring combined heat and power station in the megalopolis territory

open access: yesMATEC Web of Conferences, 2016
The first developed method allowed to determine the combined effects of emissions of pollutants into the atmospheric air in the city by combined heat and power stations group, as well as to assess the interference impact of combined heat and power ...
Telichenko Valeriy   +2 more
doaj   +1 more source

Improve the flexibility provided by combined heat and power plants (CHPs) – a review of potential technologies

open access: yese-Prime: Advances in Electrical Engineering, Electronics and Energy, 2021
The rapid growth of intermittent renewable energy for electricity production brings a huge challenge to keep the balance between supply and demand in power systems, which further raises the need of flexibility.
Chaudhary Awais Salman   +3 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

District heating system operation in power systems with high share of wind power

open access: yesJournal of Modern Power Systems and Clean Energy, 2017
The integration of continuously varying and not easily predictable wind power generation is affecting the stability of the power system and leads to increasing demand for balancing services.
Ilias DIMOULKAS   +2 more
doaj   +1 more source

Economic Dispatch of Combined Heat and Power Energy Systems Using Electric Boiler to Accommodate Wind Power

open access: yesIEEE Access, 2020
It is of significant economic value to use an electric boiler to coordinate the heating network and power grid to reduce wind curtailment during heating supply seasons in the north area.
Bo Liu   +6 more
doaj   +1 more source

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