Results 161 to 170 of about 666,236 (309)

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

A comparison between the planned and actual external loads experienced during training in a professional, male basketball team. [PDF]

Front Psychol
Scanlan AT, Smith C, Shirley S, Bartlett R, Elsworthy N, Zhang S, Ferioli D, Ibáñez SJ, Guy JH.   +8 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Modeling method and verification of interface contact stiffness based on micro-surface morphology detection. [PDF]

PLoS One
Lu S, Feng B, Chen Y.
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

ASME-Based Structural Assessment of Head-Shell Junctions in Pressurized Railway Tank Wagons. [PDF]

Materials (Basel)
Ilincă CN, Doukeh R, Ramadan IN, Neacsa A, Diniță A, Laudacescu EV, Petrescu MG, Ilie B, Sîrbu AC.   +8 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Bacterial Load of <i>Gardnerella</i> spp. and <i>Fannyhessea vaginae</i> and Its Association with Cervicovaginal Inflammatory Cytokine Responses Across Vaginal Microbiota Patterns. [PDF]

Microorganisms
Yonezawa LE, Sena Baptista Ferreira J, Tesini Rocha ME, Gomes Barnabé R, Miot HA, da Rocha Tristão A, Marconi C, de Castro Silva M, Guimarães da Silva M.   +8 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Field Investigation of Traffic Characteristics in Africa Based on an Integrated Dynamic Traffic Monitoring System. [PDF]

Sensors (Basel)
Chen Z, Du X, Chen Y, Zhang Z, Bai Z, Pei Z, Yi J.   +6 more
europepmc   +1 more source