BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Comparative quantification of Leishmania infantum in experimental phlebotomine sand fly infections using kDNA and single-copy Meta-1 gene qPCR assays. [PDF]
Porcelli S +6 more
europepmc +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Experimental Determination of Material Behavior Under Compression of a Carbon-Reinforced Epoxy Composite Boat Damaged by Slamming-like Impact. [PDF]
Altunsaray E +3 more
europepmc +1 more source
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
An optimization method for integrated demand response strategies for electricity and heat considering the uncertainty of user-side loads. [PDF]
Li J +6 more
europepmc +1 more source
Experimental research on the fire resistance of columns in container-style steel modular buildings. [PDF]
Duan J, Liu J, Wei J, Wu H, Gao S.
europepmc +1 more source
Dynamic response analysis of semi-rigid asphalt pavement under combined low-temperature and heavy-load conditions. [PDF]
Gai J +6 more
europepmc +1 more source
Biomechanical Comparative Evaluation of Atrophic Edentulous Maxilla Rehabilitation Using the All-on-Six Concept with Zygomatic Implant and Tilted Implant as Posterior Implant-Finite Element Analysis. [PDF]
Datarkar A +5 more
europepmc +1 more source
Adaptive energy management in smart homes through fuzzy reinforcement learning and metaheuristic optimization algorithms to minimize costs. [PDF]
Hamedani MMK +3 more
europepmc +1 more source

